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首页> 外文期刊>The Open Obesity Journal >Intraperitoneal Adipose Tissue: Associated Health Risks, Quantification by Advanced Imaging Methods and Future Directions in Children
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Intraperitoneal Adipose Tissue: Associated Health Risks, Quantification by Advanced Imaging Methods and Future Directions in Children

机译：腹膜内脂肪组织：相关的健康风险，先进的成像方法定量和儿童的未来发展方向

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The prevalence of obesity continues to grow at an alarming rate and currently there are no highly effectivelong-term treatments for obesity at the population level. Targeting childhood is a critical component of the strategy forfighting the obesity epidemic and there is an important need to understand the relationship among adipose tissuedistribution, growth and obesity-related health risks. Growing evidence supports the idea that visceral adipose tissue(VAT) is related to insulin resistance, metabolic syndrome, cardiovascular disease, diabetes and other medical conditionsthrough blood drainage, hormonal factors, inflammation, and adipocytokines. Recent studies suggest that VAT is not ahomogenous depot. Intraperitoneal and extraperitoneal adipose tissues (IPAT & EPAT), the two subcomponents of VAT,have different venous blood drainage and may also differ in their associations with metabolic risk. The majority ofprevious studies have used imaging methods to measure the total amount of VAT. Few studies have established protocolsfor the analysis IPAT and EPAT and those that have are limited by their approximate nature and relatively largemeasurement error. To better understand the role of adipose tissue distribution in relation to the health consequences ofobesity, accurate methods to separately measure IPAT and EPAT should be developed. Fortunately, children'scharacteristic VAT distribution permits easier differentiation between IPAT and EPAT than in adults. Future studies needto elaborate the role of regional VAT in growth and obesity with accurate quantification of IPAT and EPAT by advancedmagnetic resonance imaging methods.
机译：肥胖的患病率继续以惊人的速度增长，并且目前在人群水平上没有高度有效的长期肥胖治疗方法。以儿童为目标是对抗肥胖病流行战略的重要组成部分，并且非常需要了解脂肪组织分布，生长与肥胖相关的健康风险之间的关系。越来越多的证据支持内脏脂肪组织（VAT）与胰岛素抵抗，代谢综合征，心血管疾病，糖尿病和其他通过血液排泄，激素因子，炎症和脂肪细胞因子引起的其他疾病有关的想法。最近的研究表明，增值税不是统一的仓库。腹膜内和腹膜外脂肪组织（IPAT和EPAT）是VAT的两个子组件，具有不同的静脉血液排出，并且在与代谢风险的关联上也可能不同。大多数以前的研究已经使用成像方法来测量增值税的总额。很少有研究建立用于分析IPAT和EPAT的协议，而那些协议由于其近似性质和相对较大的测量误差而受到限制。为了更好地了解脂肪组织分布与肥胖对健康的影响有关的作用，应该开发分别测量IPAT和EPAT的准确方法。幸运的是，儿童的特征性增值税分配使IPAT和EPAT的区分比成人容易。未来的研究需要通过先进的磁共振成像方法来准确定量IPAT和EPAT，从而阐明区域性VAT在生长和肥胖中的作用。

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