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A Diet and Exercise Intervention during Chemotherapy for Breast Cancer

机译:乳腺癌化疗期间的饮食和运动干预

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Weight gain is an important concern that impacts on breast cancer outcomes and general health in survivorship.This randomized, pilot study evaluated whether or not women could comply with a weight control program that isinitiated at the beginning of chemotherapy for breast cancer. The program sought to prevent weight gain using a low-fat,high fruit-vegetable diet combined with moderate physical activity. The intervention was implemented using a telephonecounseling approach that blended motivational interviewing with social cognitive theory. A total of 40 women wererecruited over 9 months at the University of Michigan Comprehensive Cancer Center. This represents 55% of eligiblewomen referred to the study and indicates that interest in a healthy lifestyle program at the initiation of chemotherapy forbreast cancer was high. Subjects who dropped out had significantly lower fruit and vegetable intakes and lower bloodcarotenoids at baseline than subjects who completed the study. Statistically significant beneficial effects were observed onfruit and vegetable intakes, physical activity and breast cancer-specific well-being by the intervention. Mean body fatfrom dual energy X-ray absorptiometry increased in the written materials arm and decreased in the intervention arm. Ofthe enrolled women, 75% completed 12 months on study and satisfaction with study participation was high. These dataindicate that lifestyle intervention during breast cancer treatment is feasible during treatment with chemotherapy for breastcancer and benefits women in several domains.
机译:体重增加是一个重要问题,会影响乳腺癌的预后和生存状况。这项随机,先导研究评估了妇女是否可以遵守在乳腺癌化疗开始时就开始的体重控制计划。该计划试图通过低脂,高果蔬饮食和适度的体育锻炼来防止体重增加。干预是通过电话咨询方法实现的,该方法将动机访谈与社会认知理论相结合。密歇根大学综合癌症中心在9个月内招募了40名女性。这代表该研究中55%的合格女性,并且表明对乳腺癌化疗开始时对健康生活方式计划的兴趣很高。与完成研究的受试者相比,辍学的受试者在基线时的水果和蔬菜摄入量和血类胡萝卜素水平明显降低。干预措施对水果和蔬菜的摄入量,体育锻炼和特定于乳腺癌的健康具有统计学上的显着有益作用。双能X线吸收法测定的平均体脂在书面材料组增加,在干预组减少。在登记的妇女中,有75%的人完成了12个月的学习,对研究的满意度很高。这些数据表明在乳腺癌治疗期间的生活方式干预在乳腺癌化学疗法治疗期间是可行的,并且在多个领域中使妇女受益。

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