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首页> 外文期刊>The Open Bioactive Compounds Journal >High-Lycopene Tomato Intake Increases Serum Carotenoid Levels but not Biomarkers of Oxidative Stress and Inflammation in Healthy Adults
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High-Lycopene Tomato Intake Increases Serum Carotenoid Levels but not Biomarkers of Oxidative Stress and Inflammation in Healthy Adults

机译：高番茄红素番茄摄入量会增加健康成年人的血清类胡萝卜素水平，但不会增加氧化应激和炎症的生物标志物

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摘要

Fresh tomatoes higher in lycopene content than standard varieties have recently been designed. We hypothesized that consumption of fresh, high lycopene tomatoes (HEC) for 3-weeks, as compared to standard fresh tomatoes, (LEC) would result in significant increases in serum lycopene and reductions in oxidative stress and inflammation. Forty healthy adult men (37.5%) and women (62.5%) age 55.3±4.7 years (BMI = 25.1±3.3 kg/m2) completed this randomized, crossover, controlled tomato intervention. Serum lycopene, oxidative stress (8-OHdG, 8-iso-PGF2α) and inflammation (hsCRP) were assessed. Significant increases were seen in trans- and cis-lycopene (pre- and post-intervention, P < 0.0001), with cis-lycopene increasing significantly more during HEC consumption as compared to LEC (P=0.03). No significant changes in 8-OHdG, 8-iso-PGF2α or hsCRP were demonstrated. Consumption of HEC tomatoes resulted in significant elevations in serum lycopene but not significant reductions in oxidative stress or inflammation in this healthy adult population.
机译：最近设计了番茄红素含量比标准品种高的新鲜番茄。我们假设与标准新鲜番茄（LEC）相比，食用新鲜高番茄红素西红柿（HEC）3周会导致血清番茄红素显着增加，并减少氧化应激和炎症。 40名健康的成年男性（37.5％）和女性（62.5％）年龄55.3±4.7岁（BMI = 25.1±3.3 kg / m2）完成了这种随机，交叉，受控的番茄干预。评估血清番茄红素，氧化应激（8-OHdG，8-异-PGF2α）和炎症（hsCRP）。反式和顺式番茄红素的显着增加（干预前和后，P <0.0001），与LEC相比，HEC消费期间顺式番茄红素的增加更多（P = 0.03）。在8-OHdG，8-iso-PGF2α或hsCRP中未发现明显变化。在这个健康的成年人口中，食用HEC西红柿导致血清番茄红素显着升高，但氧化应激或炎症并未显着降低。

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