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首页> 外文期刊>Therapeutic advances in cardiovascular disease. >Endomyocardial biopsy-integrating electrode at the bioptome tip
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Endomyocardial biopsy-integrating electrode at the bioptome tip

机译：活检钳尖端的心内膜活检整合电极

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摘要

The addition of electroanatomic mapping to a standard echo-guided endomyocardial biopsy could identify areas of abnormal pathology and increase the diagnostic yield of the procedure. In this demonstration of a novel technique, a 45-year-old woman with clinical suspicion for cardiac sarcoidosis underwent right ventricular bipolar electroanatomical mapping with identification of areas of signal fractionation and low voltage. A bioptome, configured to record an electrogram from the tip, was then visualized on the three-dimensional electroanatomic mapping (3DEAM) system, and directed to these areas. The biopsy was assisted by the use of a steerable introducer sheath, and by recording unipolar and extended bipolar signals from the bioptome tip. A prominent change in the signal was detected by the electrode at the bioptome tip when the jaws closed on the endomyocardial tissue. Patient tolerated the procedure without complications, and the biopsied samples were appropriate for pathological analysis. Using existing technology, the 3DEAM, which integrates unipolar and bipolar signal from the bioptome tip, is feasible, and can be safely added to a standard echocardiographically guided endomyocardial biopsy. Future studies should investigate whether such a technique could increase the safety and diagnostic yield of endomyocardial biopsies in patients with suspected cardiomyopathies.
机译：在标准回声引导下的心内膜活检中添加电解剖图可以识别异常病理区域并提高该过程的诊断率。在这项新技术的演示中，一名45岁临床怀疑心脏结节病的妇女接受了右心室双极电解剖标测，确定了信号分级和低电压区域。然后，在三维电解剖标测（3DEAM）系统上可视化一个活检钳，该活检钳被配置为从尖端记录电描记图，并将其指向这些区域。活检通过使用可操纵的导引鞘，并记录来自活检钳尖端的单极和扩展双极信号来辅助。当颌骨在心内膜组织上闭合时，活检钳尖端的电极检测到信号的显着变化。患者耐受手术，无并发症，活检样本适合进行病理分析。使用现有技术，整合来自活检钳尖端的单极和双极信号的3DEAM是可行的，并且可以安全地添加到标准的超声心动图引导的心内膜活检中。未来的研究应调查这种技术是否可以增加可疑心肌病患者的心内膜活检的安全性和诊断率。

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