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首页> 外文期刊>Therapeutic advances in cardiovascular disease. >The new patent foramen ovale occluder FIGULLA in complex septal anatomy: a case series
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The new patent foramen ovale occluder FIGULLA in complex septal anatomy: a case series

机译：复杂的间隔解剖学中的新型专利卵圆孔封堵器FIGULLA：病例系列

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The appropriate treatment strategy for secondary stroke prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) remains challenging. The aim of this study was to describe a case series of patients with PFO and complex septal anatomy who underwent percutaneous correction using a FIGULLA (Occlutech?) septal occluder (FSO). Ten consecutive patients (6 females, 4 males, mean age 41.6 ± 16.0 years, range 17–52 years; Group 1) with cryptogenetic stroke and/or transient cerebral ischemia and complex septal anatomy, as defined by intraprocedural transesophageal echocardiogram (TEE) were compared with a group of 25 patients (10 females, 15 males, mean age 43.7 ± 12.3 years; Group 2) with usual tunnel-like PFO anatomy in whom PFO was closed by an Amplatzer septal occluder (ASO; AGA?). No significant differences were noted between Group 1 and Group 2 for immediate success rate, residual intraprosthetic shunt at the end of the procedure, discharge, 1, 6 and 12 months follow up, number of attempts, procedure time, fluoroscopy time, or cardiac complication (atrial arrhythmias, device embolism). The only significant difference was shown for delivery sheath size (11 ± 2 versus 9 ± 1 F) and incidence of local hematoma (30% versus 12 %) between Group 1 and Group 2, without any clinical consequence (need of transfusion) or increase in length of stay. FSO shows high performance in patients with PFO and complex septal anatomy when compared with patients with PFO and uncomplicated atrial anatomy treated by ASO. Its favorable behavior is probably related to fabric features such as the total amount of metal and the presence of titanium.
机译：对于隐源性中风和卵圆孔未闭（PFO）的患者，用于二级卒中预防的适当治疗策略仍然具有挑战性。这项研究的目的是描述一系列病例，这些患者中有PFO和复杂的间隔解剖结构，并使用FIGULLA（Occlutech？）隔腔封堵器（FSO）进行了经皮矫正。根据手术过程中经食道超声心动图（TEE）的定义，连续进行了十例患者（6名女性，4名男性，平均年龄41.6±16.0岁，范围17-52岁;第1组）患有隐遗传性中风和/或短暂性脑缺血和复杂的间隔解剖相比之下，有25例通常采用隧道状PFO解剖的患者（10例女性，15例男性，平均年龄43.7±12.3岁;第2组）被Amplatzer隔垫（ASO; AGA？）封闭。第一组和第二组之间在立即成功率，手术结束时残留的假体内分流，出院，1、6和12个月的随访，尝试次数，手术时间，荧光检查时间或心脏并发症方面没有发现显着差异。 （房性心律不齐，装置栓塞）。第1组和第2组之间的递送鞘管大小（11±2对9±1 F）和局部血肿的发生率（30％对12％）显示出唯一显着差异，而没有任何临床后果（需要输血）或增加停留时间。与PSO和经ASO治疗的无复杂心房解剖结构的患者相比，FSO在具有PFO和复杂间隔解剖结构的患者中表现出较高的性能。它的良好性能可能与织物特征有关，例如金属总量和钛的存在。

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