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首页> 外文期刊>Therapeutic advances in endocrinology and metabolism. >Economics of gastroenteropancreatic neuroendocrine tumors: a systematic review
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Economics of gastroenteropancreatic neuroendocrine tumors: a systematic review

机译：胃肠胰腺神经内分泌肿瘤的经济学：系统评价

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Despite current interest, enthusiasm and progress in the development of therapies for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), there are substantial gaps in the published literature regarding cost-of-illness analyses, economic evaluation and budget impact analyses. Compounding the issue is that data on resource utilization and cost-effectiveness of different diagnostic and therapeutic modalities for GEP-NETs are scarce. A systematic review on the economic impact of GEP-NETs was carried out using four databases: EMBASE, PubMed, the National Health Service Economic Evaluation Database and Cochrane review. Fully published articles from January 2000 to May 2017, in English and Spanish, were included. All articles that satisfied the inclusion criteria were included in the systematic review; summary descriptive statistics were used to describe the methodological characteristics. The 14 studies selected included cost-of-illness analyses (n = 4), economic evaluations (n = 7) and budget impact analyses (n = 3). Almost all studies were performed in the United States. Healthcare costs for patients with NETs included medication, outpatient visits, hospitalizations, and check-ups/tests. Reducing adverse events is an area where cost savings could be achieved; however, there was not enough evidence on the cost impact of adverse events. There is a lack of data related to resource utilization in the field of GEP-NETs. Therefore, cost-effectiveness and budget impact studies of existing and emerging treatments are urgently needed to help the decision-making process for patients with NETs.
机译：尽管目前对胃肠道胰腺（GEP）神经内分泌肿瘤（NETs）疗法的兴趣，热情和进展不断发展，但是在已发表的文献中，有关疾病成本分析，经济评估和预算影响分析仍存在很大差距。使问题更加复杂的是，缺乏关于GEP-NETs不同诊断和治疗方式的资源利用和成本效益的数据。使用四个数据库对GEP-NETs的经济影响进行了系统的评估：EMBASE，PubMed，国家卫生服务经济评估数据库和Cochrane评估。包括2000年1月至2017年5月以英文和西班牙文发表的全文。所有符合纳入标准的文章均纳入系统评价;摘要性描述统计用于描述方法学特征。选择的14项研究包括疾病成本分析（n = 4），经济评估（n = 7）和预算影响分析（n = 3）。几乎所有研究都是在美国进行的。 NET患者的医疗保健费用包括药物，门诊就诊，住院和检查/测试。减少不良事件是可以节省成本的领域;但是，没有足够的证据表明不良事件对成本产生影响。 GEP-NET领域缺少与资源利用相关的数据。因此，迫切需要对现有和新兴治疗方法进行成本效益和预算影响研究，以帮助NETs患者进行决策。

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