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首页> 外文期刊>Translational Research in Oral Oncology >Expression of survivin in dysplasia and different grades of oral squamous cell carcinoma:
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Expression of survivin in dysplasia and different grades of oral squamous cell carcinoma:

机译：Survivin在异型增生和不同级别口腔鳞状细胞癌中的表达：

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Background:Survivin is a protein that inhibits apoptosis and regulates cell division. Studies examining the expression of survivin in oral cancer are limited. Correlation between the expression of survivin in dysplasia and different grades of oral squamous cell carcinoma (OSCC) could help us to assess its use as a biomarker.Objectives:The objectives of this research were to evaluate the expression of survivin in dysplasia and in different grades of OSCC keeping in mind that when comparison is made between these two groups, it may highlight the use of this biomarker.Method:Forty samples divided into four groups; 10 each of dysplasia, well-differentiated OSCC, moderately differentiated OSCC and poorly differentiated OSCC were selected for the study. Immunohistochemical staining for the expression of survivin protein was performed.Results:Survivin showed increased expression in OSCC as compared to dysplasia, although the result was not statistically significant. The distribution of survivin showed significan...
机译：背景：Survivin是一种抑制细胞凋亡并调节细胞分裂的蛋白质。研究Survivin在口腔癌中表达的研究非常有限。 Survivin在异型增生中的表达与不同级别的口腔鳞状细胞癌（OSCC）之间的相关性可以帮助我们评估其作为生物标志物的用途。目的：本研究的目的是评估survivin在异型增生和不同级别中的表达。 OSCC谨记，当在这两组之间进行比较时，可能会突出显示此生物标记物的使用。选择发育不良，高分化OSCC，中分化OSCC和低分化OSCC中的10个进行研究。结果：与不典型增生相比，Survivin在OSCC中的表达增加，尽管结果无统计学意义。 survivin的分布显示出重要的...

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