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首页> 外文期刊>Turkish Journal of Veterinary and Animal Sciences >Comparative efficacy of seven brands of albendazole against naturally acquired gastrointestinal nematodes in sheep in Hawassa, southern Ethiopia
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Comparative efficacy of seven brands of albendazole against naturally acquired gastrointestinal nematodes in sheep in Hawassa, southern Ethiopia

机译：埃塞俄比亚南部哈瓦萨市七个品牌的阿苯达唑对绵羊自然获得的胃肠道线虫的比较功效

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This study aimed to evaluate the efficacy of 7 brands of albendazole against gastrointestinal nematodes in naturally infected sheep in southern Ethiopia. The study included 120 local breed male sheep purchased in Hawassa. The sheep were divided into 8 groups of 15 animals each. Group 1 served as the untreated control, whereas groups 2-8 were treated with ABZ1, ABZ2, ABZ3, ABZ4, ABZ5, ABZ6, and ABZ7, respectively. Fecal samples were collected before treatment on day 0, and again on post-treatment day 12. The efficacy of all 7 brands of albendazole was determined on post-treatment day 12 based on the fecal egg count reduction test (FECRT). The results of the study show that the efficacy of 5 brands was good, whereas that of the other 2 brands was low. The observed differences in efficacy between the brands of albendazole were most likely due to variations in quality rather than the administered doses. Coprocultures from all pre- and post-treatment samples showed a predominance of Haemonchus spp. Results of a questionnaire survey indicated that the benzimidazoles are the most widely used anthelmintic family, followed by the imidazothiazoles and macrocyclic lactones. In addition, it showed that farmers in the study area were engaged in several practices that may be responsible for lowering the efficacy of anthelmintics. Additional detailed studies are required to clarify the current status of the efficacy of the anthelmintics widely used in different agroecologies, animal species, and livestock management systems in Ethiopia.
机译：这项研究旨在评估埃塞俄比亚南部自然感染绵羊的7种品牌阿苯达唑对胃肠道线虫的功效。该研究包括在Hawassa购买的120只当地品种公羊。将绵羊分为8组，每组15只动物。第1组用作未治疗的对照，而第2-8组分别用ABZ1，ABZ2，ABZ3，ABZ4，ABZ5，ABZ6和ABZ7治疗。在治疗前第0天和治疗后第12天收集粪便样品。基于粪便卵数减少试验（FECRT）在治疗后第12天测定所有7个品牌的阿苯达唑的功效。研究结果表明，五个品牌的功效良好，而其他两个品牌的功效较低。在阿苯达唑各品牌之间观察到的功效差异最可能是由于质量变化而不是给药剂量引起的。来自所有处理前和处理后样品的共培养表明，Haemonchus spp占优势。问卷调查的结果表明，苯并咪唑是使用最广泛的驱虫药家族，其次是咪唑并噻唑和大环内酯。此外，它表明研究区的农民从事了可能降低驱虫药功效的几种做法。需要进行进一步的详细研究，以阐明在埃塞俄比亚不同农业生态，动物物种和牲畜管理系统中广泛使用的驱虫药的有效性的现状。

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