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首页> 外文期刊>Turkish Journal of Veterinary and Animal Sciences >Morphological diagnosis of Johne?s disease: a case report in cattle
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Morphological diagnosis of Johne?s disease: a case report in cattle

机译：约翰病的形态学诊断：一例牛的报告

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The present case report deals with the morphological (gross and histopathological) and histochemical characterization of Johne?s disease in a cow. The carcass was presented in a hidebound condition with sunken eyes and with a history of persistent and nonresponsive diarrhea. Necropsy revealed generalized gelatinization of the visceral and peripheral fat. Thorough gross examination unveiled major pathological changes in the digestive tract. The gallbladder was distended, with severely thickened walls and blood mixed with bile. The small intestine was severely congested and the mesenteric lymph nodes were enlarged. The opening of the small intestine showed marked thickening of the intestinal walls, with a corrugated appearance. Diffuse granulomatous lesions were observed in the mesenteric lymph nodes. Histopathological examination revealed severe infiltration of intestinal layers and mesenteric lymph nodes by macrophages, lymphocytes, and epithelioid cells with multiple Langhans giant cells. Ziehl=Neelsen staining demonstrated multiple acid-fast bacilli in the cytoplasm of macrophages from impression smears.
机译：本病例报告涉及母牛约翰氏病的形态学（肉眼和组织病理学）和组织化学特征。 car体呈隐蔽状态，眼睛凹陷，有持续性和无反应性腹泻的病史。尸检显示内脏和外周脂肪普遍糊化。彻底的大体检查揭示了消化道的主要病理变化。胆囊肿胀，壁严重增厚，血液与胆汁混合。小肠严重充血，肠系膜淋巴结肿大。小肠的开口显示肠壁明显增厚，并呈波纹状。在肠系膜淋巴结中观察到弥漫性肉芽肿性病变。组织病理学检查显示巨噬细胞，淋巴细胞和上皮样细胞以及多个朗汉斯巨细胞严重浸润肠层和肠系膜淋巴结。 Ziehl = Neelsen染色显示印痕涂片在巨噬细胞的细胞质中有多个耐酸杆菌。

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