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首页> 外文期刊>Tzu Chi Medical Journal >Long-term outcome of Gamma Knife radiosurgery in patients with tiny intracanalicular vestibular schwannomas detected by three-dimensional fast imaging employing steady-state acquisition magnetic resonance
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Long-term outcome of Gamma Knife radiosurgery in patients with tiny intracanalicular vestibular schwannomas detected by three-dimensional fast imaging employing steady-state acquisition magnetic resonance

机译：稳态获取磁共振三维快速成像技术检测小导管内前庭神经鞘瘤的伽玛刀放射治疗的长期结果

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Objective To evaluate the effectiveness and long-term outcome of Gamma Knife radiosurgery (GKRS) for tiny vestibular schwannomas (VSs) detected by three-dimensional fast imaging employing steady-state acquisition magnetic resonance (3D-FIESTA MR). Materials and methods Between January and December 2004, 3D-FIESTA MR of the brain was performed in patients who had physical health examinations at the Buddhist Tzu Chi General Hospital (Hualien, Taiwan). Tiny intracanalicular VSs (defined as a tumor volume Twelve patients had GR Grade I or II hearing before GKRS, and GR I or II hearing was maintained in 11 patients. Facial and trigeminal nerve functions were preserved in all patients. The tumor control rate was 100% at a mean follow-up period of 9.8 ± 1.1 years (range, 76–126 months). One patient developed acute vertigo 1 day after GKRS, which subsided after short-term use of steroids and did not recur. Conclusion With the application of 3D-FIESTA, tiny VSs can be detected early. Because low-dose (12–14 Gy) GKRS is safe and effective for long-term control of the growth of tumors with acceptable preservation rate of hearing function, it may be worthwhile to use 3D-FIESTA to detect tiny VSs and treat the patients using GKRS.
机译：目的评估伽马刀放射外科（GKRS）对采用稳态采集磁共振（3D-FIESTA MR）进行三维快速成像检测的微小前庭神经鞘瘤（VSs）的有效性和远期疗效。材料和方法2004年1月至2004年12月之间，对在台湾慈济总医院（台湾花莲）进行了身体健康检查的患者进行了大脑的3D-FIESTA MR检查。细小管内VS（定义为肿瘤体积）12例患者在GKRS之前有GR I或II级听力，11例保持了GR I或II级听力。所有患者均保留了面部和三叉神经功能。肿瘤控制率为100 ％，平均随访期为9.8±1.1年（范围76-126个月），一名患者在GKRS后1天出现急性眩晕，在短期使用类固醇后消失，并且没有复发。对3D-FIESTA而言，可以早期发现微小的VS，因为低剂量（12-14 Gy）GKRS对于长期控制肿瘤的生长是安全有效的，并且听力功能的保留率可以接受，因此值得使用3D-FIESTA检测微小的VS，并使用GKRS治疗患者。

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