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Myelopathy: Retrospective Evaluation of Twenty-Eight Cases

机译:脊髓病:回顾性评估28例。

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Objective: Myelopathy is used to describe any neurologic deficit related to the spinal cord. Determining the etiology is important for detecting emergency situations and treating the cause.Materials and Methods: We evaluated 28 patients who were diagnosed as having and treated for myelopathy between January 2014 and January 2015 in our hospital. The clinical and laboratory findings of the patients and their response to treatment were assessed.Results: Of the 28 patients, 16 were male and 12 were female, the mean age was 48 years (range, 22-77 years). The most common initial symptoms were sensorial deficits and motor weakness. Demyelinating diseases were the most common diseases and multiple sclerosis was the most frequent etiology among demiyelinating diseases. Cervical spinal cord was the most frequent region involved in myelopathy episodes which was detected by magnetic resonance imaging on T2W images. We observed clinical improvement in 15 of the 20 patients who were treated with corticosteroids. In addition, vitamin B12 treatment led to clinical improvement in two patients who were diagnosed as having subacute combined degeneration.Conclusion: The diagnosis and etiology of myelopathy and identification of rare conditions that require emergency surgery or interventional treatments are of utmost importance.
机译:目的:脊髓病用于描述与脊髓有关的任何神经系统缺陷。确定病因对发现紧急情况和治疗病因很重要。材料和方法:我们评估了2014年1月至2015年1月间在我院被确诊患有骨髓病并已接受治疗的28例患者。结果:28例患者中,男性16例,女性12例,平均年龄48岁(范围22-77岁)。最常见的初始症状是感觉缺陷和运动无力。在脱髓鞘疾病中,脱髓鞘疾病是最常见的疾病,多发性硬化症是最常见的病因。颈脊髓是脊髓病发作中最常见的区域,这是通过在T2W图像上进行磁共振成像检测到的。我们在接受皮质类固醇治疗的20例患者中,有15例观察到了临床改善。此外,维生素B12的治疗还导致两名被诊断为亚急性合并变性的患者的临床改善。结论:脊髓病的诊断和病因以及识别需要急诊手术或介入治疗的罕见病极为重要。

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