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Snake Eyes Sign in Cervical Magnetic Resonance Imaging in a Patient with Amyotrophic Lateral Sclerosis

机译:蛇眼标志着肌萎缩性侧索硬化症患者的子宫颈磁共振成像。

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A 32-year-old man presented with one year of progressive proximal weakness of the upper right limb with fasciculation. In the last three months, he could not handle an object properly with his right hand, not wave his hand, and he said that he could not use his right hand to eat. There were no sensory symptoms, bulbar symptoms or weakness in lower limbs. There was no history of neck injury or pain. The patient’s neurologic examination showed paresis in his right shoulder abduction (at MRC grade 3/5), right arm and forearm flexion at 4/5 strength, right upper extremity deep tendon reflexes (DTR) hypoactive, and fasciculation in both shoulder muscles. An electromyography (EMG) examination determined diffuse anterior horn involvement. Sensory nerve action potentials were normal in nerve conduction velocity. Cervical spine magnetic resonance imaging (MRI) showed linear T2 intramedullary hyperintensity (C3 to C6 in sagittal section), and T1 isointense signal in anterior horn cells (Figure 1) with the snake eye sign in the transverse section (Figure 2). There was no evidence of extradural compression and gadolinium had no contrast enhancement. Neural foramens were normal and had no root compression. The patient was diagnosed as having amyotrophic lateral sclerosis (ALS). The snake eye sign shows damage to the anterior horn and has been reported to become apparent in ALS-like disease
机译:一名32岁的男子出现了一年的右上肢渐进性近端肌无力,伴有束缚。在过去的三个月中,他无法用右手正确地处理物体,不能摇动手,他说他不能用右手进食。下肢无感觉症状,延髓症状或无力。没有颈部受伤或疼痛的病史。患者的神经系统检查显示他的右肩外展轻瘫(MRC为3/5),右臂和前臂屈曲强度为4/5,右上肢深部肌腱反射(DTR)异常活跃,并且双肩肌肉都出现束缚。肌电图(EMG)检查确定弥漫性前角受累。感觉神经动作电位在神经传导速度中是正常的。颈椎磁共振成像(MRI)显示线性T2髓内高信号(矢状切面为C3至C6),前角细胞中T1等强度信号(图1),横切面为蛇眼征(图2)。没有证据表明硬膜外压迫和g没有增强对比。神经孔是正常的,没有根受压。该患者被诊断患有肌萎缩性侧索硬化症(ALS)。蛇眼迹象表明前角受损,据报道在ALS样疾病中变得明显

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