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首页> 外文期刊>World Journal of AIDS >Utility of C-Reactive Protein and Procalcitonin for Detecting Bloodstream Infection in Patients with HIV/AIDS
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Utility of C-Reactive Protein and Procalcitonin for Detecting Bloodstream Infection in Patients with HIV/AIDS

机译：C反应蛋白和降钙素在检测HIV / AIDS患者血液感染中的作用

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摘要

Human immunodeficiency virus (HIV) infected persons, are at high risk for developing a bloodstream infection. In order to evaluate the usefulness of C-reactive protein (CRP) and procalcitonin (PTC) in the detection of bloodstream infection in HIV, a case-control study was conducted from February to December 2012. PCT and CPR levels were measured in 2 groups. PCT concentrations were measured by the VIDAS??Brahms PCT assay, and CRP concentrations were determined by CRP latex. Values were calculated for both biomarkers and discriminative ability of PCT and CRP was analyzed using ROC curves. There were no significant differences between the study group and the control groups with respect to CRP levels. However, they were much higher PCT levels in patients with bacteremia. PCT showed greater discriminating ability compared to CRP, and proved to be a valuable tool for the detection of systemic bacterial infections in HIV infected patients.
机译：感染人类免疫缺陷病毒（HIV）的人处于血流感染的高风险中。为了评估C反应蛋白（CRP）和降钙素原（PTC）在检测HIV血流感染中的有用性，于2012年2月至2012年12月进行了病例对照研究。对PCT和CPR水平进行了2组测量。 PCT浓度用VIDAS-Brahms PCT测定法测定，CRP浓度用CRP胶乳测定。计算两个生物标志物的值，并使用ROC曲线分析PCT和CRP的判别能力。在CRP水平方面，研究组与对照组之间无显着差异。但是，菌血症患者的PCT水平要高得多。与CRP相比，PCT表现出更大的区分能力，并且被证明是检测HIV感染患者中全身细菌感染的有价值的工具。

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