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首页> 外文期刊>World Journal of AIDS >RNA Wave for the HIV Therapy: Foods, Stem Cells and the RNA Information Gene
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RNA Wave for the HIV Therapy: Foods, Stem Cells and the RNA Information Gene

机译：RNA波用于HIV疗法：食物，干细胞和RNA信息基因

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The microRNA (miRNA) gene is small RNA molecule, approximate 20 nucleotides (nts) in length, and also the miRNA is information in a cell as well as the mobile genetic information; therefore, when only one kind of tumor suppressor RNA information gene (Rig) was intravenously administrated, tumorigenic cells can be retuned to the normal cells in vivo. Although the processes of oncogenic have multiple ways, Rig can control its complex system, such as cell cycle with tuning to translation and transcription processing systems. In quite recent experiments, human breast milk and bovine milk have contained Rigs into their microvesicular components. Both also contain the infant nutrient elements. Further, the siRNA genes in artificial nanoparticles were delivered via oral and could restore mouse intestinal inflamemation. In general, Rigs in the diet were found stable to orally affect the digested animals, therefore, the xenotropic Rigs in Rig transgenic plants could also protect from HIV-1 infection by the edible vaccine via intestinal cells. Because orally delivered miRNA as information could be incorporated into intestinal cells and transmitted into intra- and inter-cells and between individuals to wave the system of translation and transcription. Given these mobile characters of Rigs, even though there is the xenotropic miRNA issue, edible Rig agents in plants as a vaccine would be applicable for the Rig diseases (RigDs) by the information technology-based therapy (iTBT) cooperated with system-based therapies such as stem cell therapy and chemotherapy.
机译：microRNA（miRNA）基因是小RNA分子，长度约为20个核苷酸（nts），而且miRNA是细胞中的信息以及移动遗传信息。因此，当仅静脉内施用一种肿瘤抑制RNA信息基因（Rig）时，致瘤细胞可以在体内重调为正常细胞。尽管致癌过程有多种方式，但Rig可以控制其复杂的系统，例如通过调整翻译和转录处理系统来控制细胞周期。在最近的实验中，人母乳和牛乳已将Rigs包含在其微泡成分中。两者也都含有婴儿的营养元素。此外，人工纳米颗粒中的siRNA基因通过口服传递，可以恢复小鼠肠道炎症。一般而言，发现日粮中的Rig对口头消化的动物是稳定的，因此，Rig转基因植物中的异种Rigs还可以防止可食用疫苗通过肠道细胞感染HIV-1。因为口服传递的miRNA作为信息可以整合到肠道细胞中，并传递到细胞内和细胞间以及个体之间，从而传递翻译和转录系统。考虑到钻机的这些移动特性，即使存在异种miRNA问题，通过基于信息技术的疗法（iTBT）与基于系统的疗法配合使用，植物中的食用Rig剂作为疫苗也将适用于钻机疾病（RigDs）。如干细胞疗法和化学疗法。

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