...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>World Journal of Surgical Oncology >Solitary fibrous tumour of the liver—report on metastasis and local recurrence of a malignant case and review of literature
【24h】

Solitary fibrous tumour of the liver—report on metastasis and local recurrence of a malignant case and review of literature

机译：肝孤立性纤维性肿瘤—恶性肿瘤转移和局部复发的报道及文献复习

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Solitary fibrous tumours (SFT) are neoplasms of mesenchymal origin that predominantly arise from the pleura. SFT of the liver (SFTL) are a rare occurrence with little number of cases reported in English literature. Malignant cases of hepatic SFT are an even rarer occurrence. For this reason, the prognostic evaluation of SFTLs is unknown and difficult to measure. Methods A search on English literature on “Solitary Fibrous Tumour of the Liver” was conducted on common search engines (PubMed, Google). All published articles, case reports and literature reviews and their reference lists were reviewed. Case report This paper presents a 61-year-old male who was referred to a tertiary hospital in April 2010 with marked hepatomegaly. USS, CT and MRI scans were suggestive of a neoplasm, and the patient underwent a subsegmental IVb resection in June 2010. The specimen demonstrated histological and immunohistochemical features of malignant SFTL with clear resection margins. The patient was followed up regularly for 3?years with imaging and no suggestion of recurrence. Six years after the initial surgery, the patient represented with worsening right upper quadrant pain and dyspnoea secondary to extensive tumour recurrence adjacent to the resection site and metastatic deposits in the pleura. The patient was managed symptomatically and discharged for community follow-up after palliative involvement. Conclusions SFTL are rare with only 84 cases reported in the English Literature including the present case. The average age of patients is 57.1 and occurs in females more than males (1.4:1). Most SFTLs follow a benign course, however, 17.9% of cases displayed malignant histological features. Only three cases including the current case are reported to have both local recurrence and metastasis. Surgical resection remains the mainstay of treatment and appears to be curative of most cases. The rarity of this tumour makes it difficult to evaluate its prognosis and natural course.
机译：背景孤立性纤维性肿瘤（SFT）是间充质起源的肿瘤，主要起源于胸膜。肝SFT（SFTL）很少见，英国文献中报道的病例很少。肝SFT的恶性病例很少见。由于这个原因，SFTLs的预后评估是未知的，并且难以衡量。方法在常见的搜索引擎（PubMed，Google）上搜索英文文献“肝孤立性纤维瘤”。所有发表的文章，病例报告和文献综述及其参考文献清单均经过审查。病例报告本文介绍了一位61岁的男性，该男性于2010年4月被转诊至三级医院，肝肿大。 USS，CT和MRI扫描提示有肿瘤，该患者于2010年6月进行了亚段IVb切除术。该标本显示了恶性SFTL的组织学和免疫组织化学特征，切除范围清晰。定期随访患者3年，进行影像学检查，无复发迹象。初次手术后六年，患者表现为右上腹疼痛加重和呼吸困难，继发于邻近切除部位的广泛肿瘤复发和胸膜转移性沉积。对症患者经过对症处理，姑息性介入后出院接受社区随访。结论SFTL很少见，包括本例在内的英国文献中仅报道了84例。患者的平均年龄为57.1岁，女性多于男性（1.4：1）。大多数SFTL遵循良性病程，但是，17.9％的病例显示出恶性组织学特征。据报道，包括当前病例在内的仅三个病例同时具有局部复发和转移。手术切除仍然是治疗的主要手段，并且似乎可以治愈大多数病例。这种肿瘤的稀有性使其难以评估其预后和自然病程。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号