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A Retrospective Study of Acute Poisoning in Children under 5 Years Old Admitted to Alexandria Poison Center in Egypt

机译:埃及亚历山大毒药中心收治的5岁以下儿童急性中毒的回顾性研究

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Childhood poisoning represents a major public health preventable problem worldwide. It has been identified that unintentional poisoning is the most common circumstances of poisoning in young children. Various drugs and chemical compounds have been implicated such as kerosene being the most common household agent. Aim: The current study aimed to retrospectively study acute poisoning in children less than 5 years old admitted to Alexandria Poison Center (APC) at Alexandria Main University hospital as regards; pattern of childhood poisoning (incidence and prevalence), risk factors related to poisoning accidents and the outcome. Subjects and Methods: All patients aged less than 5 years with acute poisoning admitted to Alexandria Poison Center at Alexandria Main University Hospital, Alexandria, Egypt, during the period of 8 months started from 1st January to 31st August 2012 were included in the study. Results: This retrospective study involved 620 intoxicated children which represented 20.7% of total poisoning cases admitted to APC at that period of time. The incidence of poisoning was found to be highest in children aged between 3 to 5 years old and constituted 49.1% and 39.6% of males and females respectively. The mode of poisoning was found to be accidental with no reported cases of neither homicidal nor suicidal poisonings. The most common agent of toxicity in children was found to be kerosene, followed by chlorine and cholinesterase inhibitor insecticide. The outcome of most of cases (84.5%) was recovery and discharge, with 10.5% being admitted to (Intensive Care Unit) ICU and 5% mortality rate. Conclusion: Risk factors for unintentional poisoning in children involve accessibility to hazardous chemicals and medicines caused by unsafe storage, aggressive child's behavior, unsafe storage of kerosene oil and petrol, low socioeconomic status as well as low educational level of the mother.
机译:童年中毒是全球范围内可预防的主要公共卫生问题。已经确定,无意中毒是幼儿中毒的最常见情况。已经涉及到各种药物和化合物,例如煤油是最常见的家庭用剂。目的:本研究旨在回顾性研究亚历山大总医院附属亚历山大毒物中心(APC)收治的5岁以下儿童的急性中毒;儿童中毒的发生方式(发生率和患病率),与中毒事故和后果相关的危险因素。研究对象和方法:所有自2012年1月1日至8月31日开始的8个月内入院于埃及亚历山大亚历山大亚历山大大学医院亚历山大亚历山大毒药中心的5岁以下急性中毒患者均纳入研究。结果:这项回顾性研究涉及620名中毒儿童,占该时期APC入院总中毒病例的20.7%。发现中毒的发生率在3至5岁的儿童中最高,分别占男性和女性的49.1%和39.6%。发现中毒的方式是偶然的,没有关于杀人和自杀中毒的报道。发现儿童中最常见的毒性剂是煤油,其次是氯和胆碱酯酶抑制剂杀虫剂。大多数病例(84.5%)的结局是恢复和出院,其中10.5%被送往重症监护病房(ICU),死亡率为5%。结论:儿童意外中毒的危险因素包括因不安全储存,儿童行为不当,煤油和汽油的不安全储存,低社会经济地位以及母亲受教育程度低而导致接触危险化学品和药品。

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