...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Yonsei Medical Journal >Percutaneous Interventional Treatment of Extracranial Vertebral Artery Stenosis with Coronary Stents
【24h】

Percutaneous Interventional Treatment of Extracranial Vertebral Artery Stenosis with Coronary Stents

机译：冠状动脉支架介入治疗颅外椎动脉狭窄

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Stenosis of extracranial vertebral artery (VA) is not an infrequent lesion, and it can pose a significant clinical problem. However, the standard treatment for a significant VA stenosis has still not been established. Here in this study, we report our experiences of VA stenting in 25 patients (age 56.2 ± 15.2 years, male 76%). The patients had comorbidities as follows: DM (36%), hypertension (64%), Takayasu's (12%) and Behcet's diseases (4%). There were combined involvement of other vessels such as the coronary artery (72%), carotid artery (36%), subclavian artery (32%) and the contralateral vertebral artery (24%). Indications for stenting were prior stroke or symptoms related to vertebrobasilar ischemia in 11 patients, and an asymptomatic but angiographically significant stenosis (> 70% stenosis) in 14 patients. Twenty-three balloon-expandable stents and two self-expandable stents were deployed. A drug-eluting coronary stent and distal balloon protection device were each used in one case. A technically successful procedure was achieved in all patients. The baseline reference diameter was 4.7 ± 1.3 mm, minimal luminal diameter (MLD) 1.0 ± 0.6 mm (diameter stenosis 77.8 ± 12.5%) and lesion length 6.4 ± 3.9 mm. After stenting and adjuvant dilation, the MLD was increased to 4.5 ± 0.9 mm (diameter stenosis 3.1 ± 17.9%). There were no procedure-related complications. During the further follow-up period of 25 (3-49) months, no stroke or death occurred. Restenosis was observed in 4 (30.8%) of 13 eligible patients. In conclusion, VA stenting is feasible with a high degree of technical success, and this treatment is associated with a relatively low incidence of procedure-related complications. However, a relative high rate of in-stent restenosis remains as a problem to be resolved.
机译：颅外椎动脉狭窄（VA）并非罕见病变，它可能会引起严重的临床问题。但是，尚未建立用于严重VA狭窄的标准治疗方法。在本研究中，我们报告了25例患者的VA支架置入的经验（年龄56.2±15.2岁，男性76％）。患者的合并症如下：DM（36％），高血压（64％），Takayasu病（12％）和Behcet病（4％）。合并有其他血管的累及，例如冠状动脉（72％），颈动脉（36％），锁骨下动脉（32％）和对侧椎动脉（24％）。支架置入的适应症为11例患者的中风或与椎基底动脉缺血相关的症状，以及14例患者无症状但血管造影显着的狭窄（> 70％狭窄）。部署了二十三个球囊扩张支架和两个自扩张支架。在一种情况下，分别使用了一种药物洗脱冠状动脉支架和远端球囊保护装置。在所有患者中均取得了技术上成功的手术。基线参考直径为4.7±1.3毫米，最小腔直径（MLD）为1.0±0.6毫米（直径狭窄为77.8±12.5％），病变长度为6.4±3.9毫米。支架置入和辅助扩张后，MLD增至4.5±0.9毫米（直径狭窄3.1±17.9％）。没有与手术相关的并发症。在接下来的25（3-49）个月的随访期内，未发生中风或死亡。 13例合格患者中有4例（30.8％）出现再狭窄。总之，VA支架置入术是可行的，具有很高的技术成功率，并且这种治疗方法与手术相关并发症的发生率相对较低。然而，支架内再狭窄的相对较高的比率仍然是要解决的问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号