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首页> 外文期刊>Health Services Insights >Opinions on Drug Interaction Sources in Anticancer Treatments and Parameters for an Oncology-Specific Database by Pharmacy Practitioners in Asia
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Opinions on Drug Interaction Sources in Anticancer Treatments and Parameters for an Oncology-Specific Database by Pharmacy Practitioners in Asia

机译：关于亚洲药剂师针对肿瘤专科数据库中抗癌治疗药物相互作用来源和参数的意见

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Cancer patients undergoing chemotherapy are particularly susceptible to drug-drug interactions (DDIs). Practitioners should keep themselves updated with the most current DDI information, particularly involving new anticancer drugs (ACDs). Databases can be useful to obtain up-to-date DDI information in a timely and efficient manner. Our objective was to investigate the DDI information sources of pharmacy practitioners in Asia and their views on the usefulness of an oncology-specific database for ACD interactions. A qualitative, cross-sectional survey was done to collect information on the respondents’ practice characteristics, sources of DDI information and parameters useful in an ACD interaction database. Response rate was 49%. Electronic databases (70%), drug interaction textbooks (69%) and drug compendia (64%) were most commonly used. Majority (93%) indicated that a database catering towards ACD interactions was useful. Essential parameters that should be included in the database were the mechanism and severity of the detected interaction, and the presence of a management plan (98% each). This study has improved our understanding on the usefulness of various DDI information sources for ACD interactions among pharmacy practitioners in Asia. An oncology-specific DDI database targeting ACD interactions is definitely attractive for clinical practice.
机译：接受化学疗法治疗的癌症患者特别容易受到药物相互作用的影响。从业人员应及时了解最新的DDI信息，尤其是涉及新的抗癌药物（ACD）的信息。数据库对于及时有效地获取最新的DDI信息很有用。我们的目标是调查亚洲药房从业人员的DDI信息来源，以及他们对肿瘤学专用数据库对ACD相互作用的实用性的看法。进行了定性，横断面调查，以收集有关受访者的实践特征，DDI信息的来源以及在ACD交互数据库中有用的参数的信息。回应率为49％。最常用的是电子数据库（70％），药物相互作用教科书（69％）和药物概要（64％）。多数（93％）指出，适合ACD交互作用的数据库非常有用。数据库中应包括的基本参数是所检测到的交互的机制和严重性，以及是否存在管理计划（每个计划98％）。这项研究提高了我们对各种DDI信息源对亚洲药房从业人员进行ACD交互作用的理解。针对ACD相互作用的肿瘤学专用DDI数据库对于临床实践绝对有吸引力。

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