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首页> 外文期刊>Hong Kong Journal of Paediatrics >Diagnosing Enteroviral Meningitis Using Real-time RT-PCR with Cerebrospinal Fluid and Stool Specimens
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Diagnosing Enteroviral Meningitis Using Real-time RT-PCR with Cerebrospinal Fluid and Stool Specimens

机译：实时RT-PCR结合脑脊液和粪便标本诊断肠病毒性脑膜炎

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摘要

Enteroviral infections are common among children and are a main cause of meningitis. Cerebrospinalfluid (CSF) analysis is important for diagnosing meningitis, although CSF sampling is difficult and timeconsuming.In contrast, stool testing provides simpler sampling and a higher positive rate. We performedpolymerase chain reaction testing for paediatric patients (≤18 years old) who were admitted to CheonanDankook University Hospital during 2011-2015 for suspected meningitis (942 patients, 1,884 specimens).The stool specimens exhibited the highest positive rate, and 114 patients exhibited positive CSF and stoolspecimens. Fourteen patients had positive CSF specimens and negative stool specimens, while 101 patientshad positive stool specimens and negative CSF specimens. CSF analysis combined with stool testing mayprovide a more efficient and accurate diagnosis of enteroviral meningitis, compared to only CSF or stooltesting.
机译：肠病毒感染在儿童中很普遍，是脑膜炎的主要原因。尽管脑脊液采样困难且耗时，但脑脊液（CSF）分析对于诊断脑膜炎很重要。相反，粪便检测可提供更简单的采样和更高的阳性率。我们对2011-2015年因病性脑膜炎而入院的韩国天国大学医院的18岁以下小儿进行了聚合酶链反应测试（942例，1,884例），粪便样本阳性率最高，114例阳性脑脊液和粪便标本。 14名患者的CSF标本阳性和粪便阴性，而101名患者的粪便标本阳性和CSF阴性。与仅CSF或粪便检查相比，CSF分析与粪便检查相结合可提供更有效，更准确的肠病毒性脑膜炎诊断。

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