• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Hong Kong Journal of Paediatrics >A Retrospective Study Between Type I Cystic Biliary Atresia and Infantile Choledochal Cyst at a Tertiary Centre
【24h】

A Retrospective Study Between Type I Cystic Biliary Atresia and Infantile Choledochal Cyst at a Tertiary Centre

机译：第三中心I型囊性胆道闭锁与小儿胆总管囊肿的回顾性研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose : Type I cystic biliary atresia (CBA) is an uncommon variant of biliary atresia (BA) which is liable to misdiagnosis as infantile choledochal cyst (ICC). We assessed our experience with type I CBA and compared with that of ICC. Methods: Seven patients (4 males and 3 females) with type I CBA, receiving liver function detection, radiological imaging studies, liver/cyst histological examinations and radical surgery, were compared with 23 ICC patients (14 males and 9 females) admitted in our division during a 6-year period. Findings: The mean levels of total bilirubin (T-Bil), direct bilirubin (D-Bil), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (AKP) in the type I CBA group were significantly higher than those in the ICC group (p<0.01). The mean diameter of the cyst in the type I CBA group was significantly smaller than that in the ICC group (p<0.01). All 7 patients in the type I CBA group were accurately diagnosed by magnetic resonance cholangiopancreatography (MRCP) preoperatively, being in accordance with the results of intraoperative cholangiography and liver/cyst histology. Six cysts (85.7%) in the type I CBA group had a fibroinflammatory wall with no biliary epithelial lining while all 23 (100%) cysts in the ICC group had normal biliary epithelial lining. Six infants (85.7%) with type I CBA cleared their jaundice (total bilirubin ≤20 μmol/L) within 6 months after a Kasai portoenterostomy or hepaticojejunostomy procedure. All patients with ICC were in good condition with no jaundice and cholangitis after the operation. Conclusions: While elevated T-BIL/D-BIL and AST/ALT/AKP as well as smaller gallbladder/extrahepatic cyst imply type I CBA, MRCP can provide further effective assistance in making a relatively accurate diagnosis before operation. Either hepaticojejunostomy or Kasai portoenterostomy could be chosen as an optimal procedure in the treatment of type I CBA.
机译：目的：I型胆囊闭锁症（CBA）是胆道闭锁症（BA）的罕见变体，容易被误诊为婴儿胆总管囊肿（ICC）。我们评估了我们使用I型CBA的经验，并与ICC进行了比较。方法：将接受肝功能检测，放射影像学检查，肝/囊肿组织学检查和根治性手术的7例I型CBA患者（男4例，女3例）与我院收治的23例ICC的患者（男14例，女9例）进行比较。在六年的时间里划分。结果：I型CBA组的总胆红素（T-Bil），直接胆红素（D-Bil），丙氨酸氨基转移酶（ALT），天冬氨酸氨基转移酶（AST）和碱性磷酸酶（AKP）的平均水平显着高于那些在ICC组中（p <0.01）。 I型CBA组的囊肿平均直径明显小于ICC组（p <0.01）。根据术中胆管造影和肝/囊肿组织学检查的结果，术前通过磁共振胰胆管造影（MRCP）对I型CBA组的所有7例患者进行了准确诊断。 I型CBA组中有6个囊肿（占85.7％）具有纤维性炎症壁，无胆管上皮衬里，而ICC组中所有23个（100％）囊肿均具有正常的胆管上皮衬里。在进行开赛肠胃肠吻合术或肝空肠吻合术后的6个月内，有6名IBA婴儿（85.7％）清除了黄疸（总胆红素≤20μmol/ L）。所有ICC患者术后状况良好，无黄疸和胆管炎。结论：虽然T-BIL / D-BIL和AST / ALT / AKP升高，以及胆囊/肝腹囊肿变小，提示I型CBA，但MRCP可以为手术前的相对准确诊断提供进一步的有效帮助。肝空肠造口术或开赛肠胃造口术可以选择作为治疗I型CBA的最佳方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号