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首页> 外文期刊>Hong Kong Journal of Paediatrics >A Retrospective Study on Clinical Characteristics of Paediatric Crohn's Disease
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A Retrospective Study on Clinical Characteristics of Paediatric Crohn's Disease

机译：小儿克罗恩病临床特征回顾性研究

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Objectives: The aim of this study is mainly to describe the clinical pattern of paediatric Crohn's disease (CD) and improve diagnostic accuracy and therapeutic efficacy. Methods: CD patients between the ages of 0 and 18 years old were identified by survey of computerised medical information. Twenty cases were selected for this retrospective study. Results: The median age at diagnosis was 9.4 years (range, 25 days-17 years). The peak prevalence of CD was observed in the 10-14 years old age group. Sixty (50%) were males. All the children are Han Chinese ethnicity. The most common presenting symptoms was diarrhoea (70%), fever (60%), abdominal pain (55%) and bloody stool (10%). At least one extra-intestinal manifestations occurred in 35% of Crohn's disease patients. Growth retardation is another common complication, which is presented in 50% of patients. The most common distribution were ileo-colon (45%) and colon (35%). Perianal disease also occurred in 25% children with CD. According to the laboratory findings, anaemia presented in 70% patients, thrombocytosis presented in 70% and hypoalbuminaemia presented in 65%. Three patients underwent the surgery, after which death was caused in 2 cases. Conclusion: The clinical features of paediatric Crohn's disease are found to be complicated and nonspecific. Recognition of CD by paediatricians is necessary for proper diagnosis and management.
机译：目的：本研究的目的主要是描述小儿克罗恩病（CD）的临床模式并提高诊断准确性和治疗效果。方法：通过计算机医学信息调查，确定0至18岁的CD患者。该回顾性研究选择了20个病例。结果：诊断时的中位年龄为9.4岁（范围为25天至17岁）。在10-14岁年龄段的人群中，CD的患病率最高。男性为60（50％）。所有的孩子都是汉族。最常见的症状是腹泻（70％），发烧（60％），腹痛（55％）和血便（10％）。 35％的克罗恩病患者中至少有一种肠道外表现。生长迟缓是另一常见并发症，在50％的患者中出现。最常见的分布是回肠（45％）和结肠（35％）。 25％的CD儿童还发生肛周疾病。根据实验室发现，70％的患者出现贫血，70％的患者出现血小板增多症，65％的患者出现低白蛋白血症。 3例患者接受了手术，此后2例死亡。结论：发现小儿克罗恩病的临床特征复杂且无特异性。儿科医生对CD的识别对于正确的诊断和管理是必要的。

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