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首页> 外文期刊>Hormones: International Journal of Endocrinology and Metabolism >Bilateral versus unilateral papillary thyroid microcarcinoma: predictive factors and associated histopathological findings following total thyroidectomy
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Bilateral versus unilateral papillary thyroid microcarcinoma: predictive factors and associated histopathological findings following total thyroidectomy

机译:双侧甲状腺与单侧甲状腺乳头状微癌:全甲状腺切除术后的预测因素和相关的组织病理学发现

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OBJECTIVE: The extent of thyroidectomy for papillary thyroid microcarcinoma (PTMC) is debatable. This study investigated the rate and predictive factors of bilateral versus unilateral PTMC with the objective of identifying those patients who may benefit from total thyroidectomy. DESIGN: Between January 2001 and December 2008, 2019 patients who underwent total thyroidectomy were examined. A total of 319 patients diagnosed histopathologically as PTMC were included in the study. The predictive value of age at diagnosis, gender, tumor size, multifocality, lymph node metastasis, thyroid capsule invasion and nonincidental diagnosis using univariate and multivariate analyses were retrospectively analyzed. RESULTS: Of the 319 patients with PTMC, 77 (24.1%) presented bilateral disease. In univariate analysis, size of tumor ≥5mm (p
机译:目的:甲状腺乳头状微癌(PTMC)甲状腺切除术的范围尚有争议。这项研究调查了双边和单侧PTMC的发生率和预测因素,目的是确定哪些患者可能会从全甲状腺切除术中受益。设计:在2001年1月至2008年12月之间,对2019年接受全甲状腺切除术的患者进行了检查。该研究共包括319名经组织病理学诊断为PTMC的患者。回顾性分析了单因素和多因素分析对诊断,性别,肿瘤大小,多灶性,淋巴结转移,甲状腺包膜浸润和意外诊断的预测价值。结果:在319例PTMC患者中,有77例(24.1%)出现了双侧疾病。单因素分析中,肿瘤大小≥5mm(p

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