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首页> 外文期刊>Hong Kong Journal of Paediatrics >Overweight and Obesity in Children Under Phenylalanine Restricted Diet
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Overweight and Obesity in Children Under Phenylalanine Restricted Diet

机译：苯丙氨酸限制饮食下儿童的超重和肥胖

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Introduction: The aim of this study is to determine the obesity and overweight frequency in children withphenylketonuria (PKU) and hyperphenylalaninaemia (HPA). Methods: From the patients' demographicdata, diagnosis, type of diet, weight for height, body mass index, serum phenylalanine concentrationswere obtained and recorded. Results: Four hundred and forty charts were evaluated and 288 of themwere enrolled in the study. Two hundred and forty-six (85.4%) were under phenylalanine-restricted dietwith protein support. Of those, 23 (9.3%) were obese and 16 (6.5%) were overweight. When we comparedthe obesity ratio of 246 patients with PKU and HPA to the obesity ratio in the Turkish population, thedifference was statistically significant (p=0.025). Conclusion: The frequency of obesity was higher inPKU and HPA children who underwent phenylalanine-restricted diet treatment than in the normalpopulation in Turkey. Detailed studies are needed to increase the understanding of the obesity risk factorsin this special disorder group.
机译：简介：本研究的目的是确定苯丙酮酸尿症（PKU）和高苯丙氨酸血症（HPA）儿童的肥胖和超重频率。方法：从患者的人口统计学数据中，获取并记录诊断，饮食类型，身高体重，体重指数，血清苯丙氨酸浓度。结果：评估了440张图表，其中288张被纳入研究。 246位（85.4％）的人接受了蛋白质支持的苯丙氨酸限制饮食。在这些人中，有23人（9.3％）肥胖，而16人（6.5％）超重。当我们将246名PKU和HPA患者的肥胖率与土耳其人群中的肥胖率进行比较时，差异具有统计学意义（p = 0.025）。结论：接受苯丙氨酸限制饮食治疗的PKU和HPA儿童的肥胖发生率高于土耳其的正常人群。需要进行详细的研究以增加对该特殊疾病组中肥胖危险因素的了解。

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