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Bubble CPAP for Preterm Infants with Respiratory Distress: A Meta-analysis

机译：Bubble CPAP用于患有呼吸窘迫的早产儿：一项荟萃分析

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Objective: A meta-analysis evaluated bubble continuous positive airway pressure (bCPAP) for respiratory distress and investigated the effectiveness and safety of bCPAP in the management of preterm infants via the rate of continuous positive airway pressure (CPAP) failure, the duration of CPAP, the duration of hospital stay and complications. Methods: Randomised controlled trials which compared bCPAP with continuous flow CPAP or variable flow CPAP on preterm infants were searched in electronic literature databases PubMed?, Embase?, Web of Science and Cochrane Library. The CPAP failure rate and incidence of complications was measured by the Risk Ratio (RR) with 95% confidence intervals (CI). The duration of CPAP (hr) and hospital stay (d) was measured by the mean difference (MD) with 95% CI. Results: A total of 196 studies were identified, and 7 citations (involving 566 participants) were included finally. The 5 studies on CPAP failure rate had a pooled RR of 0.61 (95% CI: 0.39, 0.96). Four studies on duration of hospital stay showed a MD of -3.95(95%CI: -4.49, -3.41). Four studies on nasal trauma showed a RR of 2.69 (95% CI: 1.36, 5.33). Other complications were comparable in both groups. Conclusion: Bubble CPAP is as effective as the other forms of CPAP in preterm infants with respiratory distress. It reduced the CPAP failure rate and the length of hospital stay; however, it was at higher risk of nasal trauma.
机译：目的：一项荟萃分析评估了气泡持续气道正压通气（bCPAP）对呼吸窘迫的影响，并通过持续气道正压通气衰竭（CPAP）的持续时间，持续时间，持续时间，持续时间，研究了bCPAP在早产儿管理中的有效性和安全性，住院时间和并发症。方法：在电子文献数据库PubMed ？，Embase ？，Web of Science和Cochrane中检索比较早产儿bCPAP与连续流式CPAP或变流式CPAP的随机对照试验。图书馆。 CPAP失败率和并发症发生率通过风险比（RR）和95％置信区间（CI）进行衡量。通过具有95％CI的平均差异（MD）来测量CPAP的持续时间（hr）和住院时间（d）。结果：总共鉴定了196篇研究，最后包括7篇文献（涉及566名参与者）。对CPAP失败率的5项研究汇总的RR为0.61（95％CI：0.39，0.96）。四项关于住院时间的研究表明MD为-3.95（95％CI：-4.49，-3.41）。四项关于鼻外伤的研究表明，RR为2.69（95％CI：1.36、5.33）。两组其他并发症均相当。结论：泡泡CPAP在呼吸窘迫早产儿中与其他形式的CPAP一样有效。它减少了CPAP失败率和住院时间;但是，它有较高的鼻外伤风险。

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