Glomerulopathy with fibronectin deposits (GFND) is a rare glomerular disorder. We report a 28-year-old malediagnosed with GFND by mass spectrometry on kidney biopsy tissue. Whole-exome sequencing (WES) identified thata previously undescribed FN1 gene mutation (c.3051G T, p.W1017C) was likely responsible for this patient’sfibronectin glomerulopathy. We discuss the implications of this novel variant of FN1 and the importance of WES toidentify a mutation in a gene of interest.
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