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ACE I/D Gene Polymorphism in Athletes of Various Sports Disciplines

机译:不同运动学科运动员的ACE I / D基因多态性

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Purpose. Genetic factors play an important role in physical performance. In this study, the polymorphism of the angiotensin-converting enzyme gene (ACE) was analyzed in relation to the level of physical fitness, measured by maximal oxygen uptake (VO2max). Methods. Molecular genetic research on the ACE gene was carried out on a group of 154 men and 85 women. All of the subjects were Polish students at the University School of Physical Education in Poznań and included professional athletes representing various sport disciplines and levels of fitness. Results. Allele I was found to have an advantageous effect on higher maximal oxygen uptake values and, in addition, a characteristic distribution of genotypes was found, where allele II was more common in individuals practicing aerobic sports and allele DD in individuals training anaerobic disciplines. Conclusion. No significant associations were found between I/D polymorphism in the ACE gene and VO2max values but certain tendencies were found for those individuals with the ACE II genotype.
机译:目的。遗传因素在身体表现中起重要作用。在这项研究中,分析了血管紧张素转换酶基因(ACE)的多态性与身体健康水平的关系,并通过最大摄氧量(VO 2max )进行了测量。方法。 ACE基因的分子遗传学研究在154名男性和85名女性中进行。所有科目都是波兹南大学体育学院的波兰学生,其中包括代表各种运动学科和健身水平的专业运动员。结果。发现等位基因I对更高的最大摄氧量具有有利影响,此外,还发现了基因型的特征分布,其中等位基因II在从事有氧运动的个体中更常见,而在进行厌氧训练的个体中等位基因DD更常见。结论。 ACE基因的I / D多态性与VO 2max 值之间没有发现显着的关联,但是对于那些具有ACE II基因型的个体,发现了某些趋势。

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