Biokinetic datasets of PEI F25-LMW complexed and non-complexed <ce:sup loc='post'>32</ce:sup>P-siRNA within different lung compartments

Jens Lipka; Manuela Semmler-Behnke; Alexander Wenk; Jana Burkhardt; Achim Aigner; Wolfgang Kreyling

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Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments

机译：PEI F25-LMW复合和非复合 32 P-siRNA在不同肺室中的生物动力学数据集

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Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the 32 P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in “ Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice ” (Lipka et al., 2016 ).

机译：给出了不同肺区隔内经肺给药的PEI F25-LMW / siRNA复合体的生物动力学数据。因此，在三个不同的时间点（1小时，3小时，8小时），通过计算整个小鼠体内的32 P放射性来确定数据。此外，针对目标器官中可用的PEI F25-LMW / siRNA多聚体对数据进行了优化，因此将其标准化为所有肺区室的总和。方法，其他生物动力学数据和结果讨论发表在“气管内滴注小鼠后非复合siRNA与纳米级PEI F25-LMW / siRNA复合物的生物动力学研究”中（Lipka等，2016）。

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《Data in Brief》 |2016年第1期|共4页
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Jens Lipka; Manuela Semmler-Behnke; Alexander Wenk; Jana Burkhardt; Achim Aigner; Wolfgang Kreyling;
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1. Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice [J] . Lipka Jens, Semmler-Behnke Manuela, Wenk Alexander, International Journal of Pharmaceutics . 2016,第1a2期

机译：气管内滴入小鼠后非复合siRNA与纳米级PEI F25-LMW / siRNA复合物的生物动力学研究
2. Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice [J] . Lipka Jens, Semmler-Behnke Manuela, Wenk Alexander, International Journal of Pharmaceutics . 2016,第1a2期

机译：腹腔内滴注到小鼠中的非复合siRNA与纳米尺寸PEI F25-LMW / siRNA多元化的生物学研究
3. Simulated infrared and Raman spectroscopy, complex dielectric function and refractive index dataset of monoclinic C2/ m stoichiometric clinochlore Mg 6Si 4O 10(OH) 8 as obtained from Density Functional Theory [J] . Gianfranco Ulian, Daniele Moro, Giovanni Valdrè Data in Brief . 2020,第2期

机译：模拟红外和拉曼光谱，单斜晶型和斜度折射率数据集 c 2 / m 化学计量clinochlore mg 6 和 4 O 10 （哦） 8 从密度函数理论中获得
4. Preparation of PEI-Fe3O4/survivin-siRNA magnetic complex and its anti-tumor effect combined with MFH on lung carcinoma cells [C] . Xinxin Hou, Hao Zhang, Hongbo Li, The 14th Annual conference of the Chinese Society of Micro-Nano technology; The 3rd International conference of the Chinese Society of Micro-Nano technology; The 6th International workshop on innovation and commercialization of Micro amp; Nanotechnology . 2012

机译：PEI-Fe3O4 / survivin-siRNA磁性复合物的制备及其与MFH联合对肺癌细胞的抗肿瘤作用
5. The association between vitamin E intake and lung cancer risk and the effect modification of fat and fatty acid intakes on this association: A case-control study based on the NHANES datasets 1999-2010 [D] . Akrawi, Widad. 2013

机译：维生素E摄入量与肺癌风险之间的关联以及脂肪和脂肪酸摄入量对这种关联的影响调节：基于NHANES数据集1999-2010的病例对照研究
6. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments [O] . Jens Lipka, Manuela Semmler-Behnke, Alexander Wenk, 2016

机译：PEI F25-LMW复合和非复合32P-siRNA在不同肺室中的生物动力学数据集
7. Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments [O] . Jens Lipka, Manuela Semmler-Behnke, Alexander Wenk, 2016

机译：pEI F25-LmW复合和非复合32p-siRNa在不同肺隔室内的生物动力学数据集

Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments

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