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DBH2H: vertebrate head-to-head gene pairs annotated at genomic and post-genomic levels

机译:DBH2H:在基因组水平和基因组后水平注释的脊椎动物头对头基因对

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DBH2H collects head-to-head (h2h) gene pairs identified from human, mouse, rat, chicken and fugu genomes, and distinguishes the ortholog mapping relationship among them. The gene pairs in DBH2H are annotated with sequential features including single nucleotide polymorphisms, CpG islands and transcription factor binding sites, as well as functional terms and genetic disorders. In addition, the expression correlation information based on 117 microarray datasets is included. By providing user-friendly access to these data, DBH2H represents a valuable resource for further analyses of this important gene arrangement in terms of transcriptional regulation mechanisms, evolutionary conservation, disease relevance, etc. Database URL: http://lifecenter.sgst.cn/h2h/
机译:DBH2H收集从人,小鼠,大鼠,鸡和河豚基因组中鉴定的头对头(h2h)基因对,并区分它们之间的直系同源物定位关系。 DBH2H中的基因对具有顺序特征,包括单核苷酸多态性,CpG岛和转录因子结合位点,以及功能术语和遗传疾病。此外,还包括基于117个微阵列数据集的表达相关信息。通过提供对这些数据的用户友好访问,DBH2H代表了宝贵的资源,可用于在转录调控机制,进化保守性,疾病相关性等方面进一步分析这一重要的基因排列。数据库URL:http://lifecenter.sgst.cn / h2h /

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