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首页> 外文期刊>Dental Hypotheses >Comparison of the Efficacy and Side Effects of Chlorhexidine Mouthrinses with (Hexidine) and without (Epimax) Alcohol
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Comparison of the Efficacy and Side Effects of Chlorhexidine Mouthrinses with (Hexidine) and without (Epimax) Alcohol

机译：含（己定）和不含（Epimax）酒精的洗必泰漱口水的功效和副作用的比较

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Introduction: Chlorhexidine mouthrinses have widely been recognized for their contribution in maintaining plaque control. Most of them contain alcohol that makes them impractical for many patients. Alcohol-free mouthwashes may have fewer side effects but may be less efficient. The current study was aimed to compare the effectiveness and side effects of chlorhexidine mouthrinses with and without alcohol. Materials and Methods: In this double-blind clinical trial, 32 patients with moderate and severe gingivitis were recruited. For all patients, full prophylactic procedures, such as removal of plaque, calculus, and stains on the teeth, were performed. Each patient was asked to use 15 mL of the mouthrinse for 60 s twice daily. The patients were divided into two groups, one group used Hexidine (0.12% chlorhexidine and 10% ethanol) mouthwash and the other group used Epimax (0.12% chlorhexidine and 0.05% sodium fluoride) mouthwash. After 14 days, plaque (PI), gingival (GI), and stain indices were analyzed. The obtained data were analyzed by using SPSS 16 using covariance [Analysis of covariance (ANCOVA)] and t-test. Results: Both mouthwashes significantly reduced the mean scores of plaque (P P Conclusion: Although Epimax mouthwash did not show any side effects, it was less suitable and caused more dental stain. Ethanol-free Hexidine mouthwash seems to be more proper for gingivitis, but its side effects are required to be taken into consideration.
机译：简介：洗必泰漱口水因其在保持斑块控制中的作用而被广泛认可。它们中大多数含有酒精，这使它们对许多患者不切实际。无酒精漱口水可能具有较少的副作用，但效率可能较低。目前的研究旨在比较洗必泰漱口水和不加酒精的功效和副作用。材料和方法：在该双盲临床试验中，招募了32例中重度牙龈炎患者。对于所有患者，都进行了全面的预防性措施，例如去除牙菌斑，牙结石和牙齿上的污渍。要求每个患者每天两次两次使用15 mL漱口水60 s。患者分为两组，一组使用洗必泰（0.12％洗必泰和10％乙醇）漱口水，另一组使用Epimax（0.12％洗必泰和0.05％氟化钠）漱口水。 14天后，分析了牙菌斑（PI），牙龈（GI）和污渍指数。使用协方差[协方差分析（ANCOVA）]和t检验，使用SPSS 16分析获得的数据。结果：两种漱口液均显着降低了牙菌斑的平均分值（PP结论：尽管Epimax漱口液未显示任何副作用，但不适合使用，并且会导致更多的牙渍。需要考虑副作用。

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