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首页> 外文期刊>Dental Journal: Majalah Kedokteran Gigi >Effects of herbal medicine components on the physical properties of trial denture adhesives
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Effects of herbal medicine components on the physical properties of trial denture adhesives

机译：草药成分对义齿胶粘剂物理性能的影响

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Background: Denture adhesive is widely used in elderly people who wear complete dentures. Chinese herbal medicine has long been used for the treatment of oral disease. The addition of herbal medicine to denture adhesive might be used to develop an adhesive which is effective for xerostomia patients. Purpose: The purpose of this study was to evaluate physical properties and cytototoxicity of herbal medicine components in denture adhesive. Methods: This study used a combination of 35wt% PVM-MA, 20wt% CMC, 40wt% white petrolatum and 5wt% liquid paraffin as base materials. Three kinds of herbal medicine components: Maimendong (Ophiopogon), Fuling (Hoelen) and Dongkuizi (Cluster mallow seed) were added to base materials of 1wt%, 5wt% and 10wt%. The initial viscosity was measured using a controlled-stress rheometer (AR-G2). The adhesive strength was quantified according to ISO-10873 recommended procedures. All data was analyzed independently by one-way Anova combined with a Turkey’s multiple comparison test at a 5% level of significance. Results: Significant differences were observed between materials in initial viscosity (p < 0.05). Specifically, samples containing 5wt% and 10wt% of Maimendong (Ophiopogon) showed higher values compared with the control samples. The larger the amounts of herbal medicine components, the greater the changes in the adhesive strength of denture adhesives over time. The denture adhesives containing herbal medicine components do not have a cytotoxic effect and are safe for use in actual clinical practice. Conclusion: The study showed that the addition of herbal medicine components does not affect physical properties (i.e. initial viscosity and adhesive strength) of denture adhesive and cytotoxicity in fibroblast cells.
机译：背景：义齿粘合剂广泛用于佩戴全口义齿的老年人。长期以来，中草药一直用于治疗口腔疾病。向义齿粘合剂添加草药可用于开发对口干燥症患者有效的粘合剂。目的：本研究的目的是评估义齿粘合剂中草药成分的物理特性和细胞毒性。方法：本研究使用35wt％PVM-MA，20wt％CMC，40wt％白凡士林和5wt％液体石蜡的组合作为基础材料。向原料中分别添加了1wt％，5wt％和10wt％的三种草药成分：麦门冬（麦冬），Fu陵（Hoelen）和冬葵子（丛锦葵种子）。初始粘度使用控制应力流变仪（AR-G2）测量。粘合强度根据ISO-10873推荐程序进行定量。所有数据均通过单向Anova结合土耳其的多重比较测试以5％的显着性水平进行了独立分析。结果：观察到材料之间的初始粘度存在显着差异（p <0.05）。具体而言，与对照样品相比，包含5wt％和10wt％的麦门冬（麦冬）的样品显示出更高的值。草药成分的量越大，义齿粘合剂的粘合强度随时间的变化就越大。包含草药成分的义齿粘合剂没有细胞毒性作用，可以安全地用于实际临床实践中。结论：研究表明，添加草药成分不会影响义齿粘合剂的物理性质（即初始粘度和粘合强度）以及成纤维细胞的细胞毒性。

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