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Malignant Transformation of Oral Lichen Planus in Labial Location in a 23-Year-Old Woman – Case Report

机译:一名23岁妇女的唇部口腔扁平苔藓恶变–病例报告

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Abstract Lichen planus (LP) having a potential for malignant transformation is a rare mucocutaneous disease most frequently observed in middle-aged women than in men. LP is uncommon in young patients and the involvement of a labial site and desquamative gingivitis are also rare. LP mainly affects oral mucosa, and skin involvement is rare. Mucosal lesions are usually multiple and have a bilateral, symmetrical manifestation. Mucosal lesions frequently appear on the tongue, gingiva, and mucobuccal fold. Nearly half of the patients has multiple sites of involvement. Oral biopsy with a histopathological evaluation is necessary to validate the clinical diagnosis of LP. Malignant transformation is uncommon for young patients with a short history of LP and without the presence of other co-morbidities. The aim of the present report was to present a 23-year-old patient with an LP lesion which developed into a squamous cell carcinoma on a facial labial site. Different subject-related pathological, diagnostic and treatment aspects are discussed.
机译:摘要扁平苔藓(LP)具有潜在的恶性转化作用,是一种罕见的粘膜皮肤疾病,在中年女性中比男性更常见。 LP在年轻患者中并不常见,并且唇部部位受累和脱屑性牙龈炎也很少见。 LP主要影响口腔粘膜,皮肤受累很少。粘膜病变通常是多发的,具有双侧对称的表现。粘膜病变常出现在舌头,牙龈和粘膜颊沟上。近一半的患者有多个受累部位。对组织活检进行口腔活检对于验证LP的临床诊断是必要的。对于LP病史短且没有其他合并症的年轻患者,恶性转化并不常见。本报告的目的是介绍一名23岁的LP病变患者,该病变在面部唇部部位发展成鳞状细胞癌。讨论了与受试者相关的不同病理,诊断和治疗方面。

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