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首页> 外文期刊>Dental Materials Journal >Novel rechargeable calcium phosphate nanoparticle-filled dental cement
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Novel rechargeable calcium phosphate nanoparticle-filled dental cement

机译：新型可充电磷酸钙纳米颗粒填充牙胶

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摘要

The objectives were to develop a novel rechargeable cement containing amorphous calcium-phosphate nanoparticles (nanoACP) to suppress tooth decay. Five cements were made with: (1) 60% glass particles (experimental control); (2) 40% glass+20% nanoACP; (3) 30% glass+30% nanoACP; (4) 20% glass+40% nanoACP; (5) 10% glass+50% nanoACP. Groups 1–4 had enamel bond strengths similar to Transbond XT (3M) and Vitremer (3M) (p >0.1). The nanoACP cement had calcium and phosphate ion release which increased with increasing nanoACP fillers. The recharged cement had substantial ion re-release continuously for 14 days after a single recharge. Ion re-release did not decrease with increasing recharge/re-release cycles. Groups 3–5 maintained a safe pH of medium (>5.5); however, control cements had cariogenic pH of medium (<4.5) due to biofilm acid. Therefore, nanoACP cement (1) had good bond strength to enamel, (2) possessed calcium and phosphate ion recharge/re-release capability, and (3) raised biofilm pH to a safe level to inhibit caries.
机译：目的是开发一种新型的可充电水泥，其中包含无定形磷酸钙纳米粒子（nanoACP），以抑制蛀牙。用以下五种材料制成水泥：（1）60％的玻璃颗粒（实验对照）; （2）40％玻璃+ 20％纳米ACP; （3）30％玻璃+ 30％纳米ACP; （4）20％玻璃+ 40％纳米ACP; （5）10％玻璃+ 50％nanoACP。 1-4组的釉质粘结强度类似于Transbond XT（3M）和Vitremer（3M）（p> 0.1）。 nanoACP水泥的钙和磷酸盐离子释放量随nanoACP填料的增加而增加。在单次补给后，补给的水泥连续14天连续大量释放离子。离子的再释放并未随着充电/再释放周期的增加而减少。 3-5组保持中等的安全pH（> 5.5）;但是，由于生物膜酸，对照水泥的生龋pH值为中等（<4.5）。因此，nanoACP水泥（1）对牙釉质具有良好的粘结强度;（2）具有钙和磷酸根离子的充/释放能力;（3）将生物膜的pH值提高至安全水平以抑制龋齿。

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