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Oral findings in Rett syndrome: An update and review of the literature

机译：Rett综合征的口腔检查结果：文献资料的更新和回顾

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Rett syndrome is a progressive pediatric neurodevelopmental disorder, predominantly affecting females, characterized by a seemingly normal prenatal and perinatal period, followed by neurodevelopmental stagnation, and then rapid regression. The purpose of this study was to provide an update of the literature on the oral aspects of Rett syndrome and their possible treatment in patients suffering from this pathology. After an electronic and manual search in MEDLINE (PubMed) and the Cochrane Library, 12 articles were found, for a total of 142 patients affected by Rett syndrome. A high prevalence of bruxism, anterior open bite, ogival palate, sucking habits, and difficulties in maintaining oral hygiene was noted. There were also oral findings related to the pharmacological treatment, which included xerostomia, glossitis, erythema multiforme, gingival hyperplasia, dysphagia, and lingual paralysis. It is important for the dentist to know what problems related to the oral cavity can be encountered in a patient diagnosed with Rett syndrome and what preventive measures can be applied.
机译：Rett综合征是一种进行性小儿神经发育障碍，主要影响女性，特征是产前和围产期看似正常，随后是神经发育停滞，然后迅速消退。这项研究的目的是提供有关Rett综合征的口腔方面及其在患有该病的患者中可能的治疗方法的文献的最新信息。在MEDLINE（PubMed）和Cochrane图书馆中进行电子和手动搜索后，共找到142篇受Rett综合征影响的患者的12篇文章。人们发现磨牙症，前开口咬伤，齿龈上颚，吸吮习惯和维持口腔卫生的困难的患病率很高。也有与药物治疗有关的口服发现，包括口干，舌炎，多形性红斑，牙龈增生，吞咽困难和舌麻痹。对于牙医来说，重要的是要知道在诊断为Rett综合征的患者中可能遇到与口腔有关的问题以及可以采取哪些预防措施。

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