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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Biosynthesis and characterization of silver nanoparticles: Its use for bacterial detection
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Biosynthesis and characterization of silver nanoparticles: Its use for bacterial detection

机译：银纳米颗粒的生物合成和表征：其用于细菌检测

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In this study; we have designed a Silver nanoparticles (AgNps) based piezoelectric Quartz crystal microbalance (QCM) AgNPs were synthesized and were coupled with anti sera of S. typhimurium. Coupled AgNps were characterized by TEM and FITR In TEM micrographs; we have observed spherical of AgNPs at the range ~50nm diameter Developed immunosensor for S typhimurium QCM has showed good reactivity and specificity towards its antigen of S. typhimurium; also showed decrease in frequency with respect to incubation time. The developed methodology is effective; selective; inexpensive and reproducible for the detection of S. typhimurium and a further step forwards towards development of point of care technology for the detection of bacteria Moreover; we have also demonstrated that the efficacy and sensitivity of sensors could be increased by immobilization of functional nanoparticles on the surface of quartz crystal.
机译：在这个研究中;我们设计了一种基于银纳米颗粒（AgNps）的压电石英晶体微天平（QCM）AgNP，并与鼠伤寒沙门氏菌的抗血清结合。通过TEM和FITR在TEM显微照片中表征了偶联的AgNps。我们已经观察到直径约50nm的球形AgNPs。开发的用于鼠伤寒沙门氏菌QCM的免疫传感器对鼠伤寒沙门氏菌的抗原具有良好的反应性和特异性。还显示出相对于孵育时间的频率降低。制定的方法是有效的;可选择的;价格便宜且可重复用于鼠伤寒沙门氏菌的检测，并且朝着检测细菌的护理技术发展又迈进了一步;我们还证明了通过将功能性纳米颗粒固定在石英晶体表面可以提高传感器的功效和灵敏度。

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