• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >SAR and Pharmacophore Based Designing of Some Antimalarial and Antiretroviral Agents: An INTERNET Based Drug Design Approach
【24h】

SAR and Pharmacophore Based Designing of Some Antimalarial and Antiretroviral Agents: An INTERNET Based Drug Design Approach

机译：基于SAR和药理学的抗疟和抗逆转录病毒药物的设计：基于INTERNET的药物设计方法

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

With the development of computational chemistry and molecular docking studies SAR and pharmacophore based drug design have been modified to target based drug discovery using sophisticated computational tools which is not very much user friendly and has got many incompatibility issues with many operating systems(OS) and other system configurations. In this paper SAR (Structure Activity Relationship) and pharmacophore based drug design approaches have been described by the used of free internet based tools which are very much user friendly and can almost compatible with any platform. Some antimalarial. And anti retroviral agents have been designed using pharmacophore study and their drug like properties,toxicity,metabolic sites and other parameters are predicted by the free internet based tools.
机译：随着计算化学和分子对接研究的发展，已经使用复杂的计算工具将基于SAR和药效团的药物设计修改为基于目标的药物发现，该工具对用户的友好程度并不高，并且与许多操作系统（OS）和其他操作系统存在许多不兼容的问题系统配置。在本文中，已经通过使用基于Internet的免费工具描述了SAR（结构活动关系）和基于药效团的药物设计方法，这些工具非常易于使用，几乎可以与任何平台兼容。一些抗疟疾。抗逆转录病毒药物已通过药效基团研究设计出来，其药物性质，毒性，代谢部位等参数可通过基于互联网的免费工具进行预测。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号