Antibacterial study of mixed ligand chelate and its application to tuberculosis

Chitra Rekha Tiwari

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Antibacterial study of mixed ligand chelate and its application to tuberculosis

机译：混合配体螯合物的抗菌研究及其在结核中的应用

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Rifampicin, anti-tubercular drugs have been screened for their activity towards mycobacteria, Ecoli and Streptocoli.On Mycobacerium bacteriological activity have been conducted With metal chelates (complexes) of Pyrazinamide, Isoniazid and Rifampicin the results obtained were compared with that of the Parent drug. It is being shown that in many cases metal complexes were more potent than as compared with pure drug. The study revels that few metal chelates (complexes) show a remarkable resistance as compared with the Parent drug.

机译：筛选了利福平抗结核药对分枝杆菌，Ecoli和链球菌的活性。对吡嗪酰胺，异烟肼和利福平的金属螯合物（配合物）进行了分枝杆菌的细菌活性研究，将所得结果与母体药物进行了比较。结果表明，在许多情况下，金属配合物比纯药物更有效。研究表明，与母体药物相比，几乎没有金属螯合物（复合物）显示出显着的耐药性。

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《Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry》 |2012年第1期|共4页
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Chitra Rekha Tiwari;
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Antibacterial study of mixed ligand chelate and its application to tuberculosis

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