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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >UV Spectrophotometric method for estimation of oxolamine citrate from bulk drug and pharmaceutical formulation
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UV Spectrophotometric method for estimation of oxolamine citrate from bulk drug and pharmaceutical formulation

机译：紫外分光光度法从原料药和制剂中估算柠檬酸羟乙胺

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摘要

A simple , rapid, sensitive and precise UV spectrophtometric method have been developed for the estimation of oxolamine citrate from bulk drug and pharmaceutical formulation. In this method oxolamine citrate showed maximum absorbance at about 237 nm in methanol. Beer’s law was followed in the concentration range of 1 to 14 μg/ ml. Regression equation was found to be y = 0.066 x -0.0008 and coefficient of correlation was 0.9990. The proposed method is accurate, sensitive, reproducible and useful for the estimation of oxolamine citrate from bulk drug and pharmaceutical formulation.
机译：已经开发了一种简单，快速，灵敏和精确的紫外分光光度法，用于从原料药和药物制剂中估算柠檬酸羟乙胺。在该方法中，柠檬酸羟乙胺在甲醇中在约237 nm处显示最大吸光度。遵循比尔定律，浓度范围为1至14μg/ ml。发现回归方程为y = 0.066 x -0.0008，相关系数为0.9990。所提出的方法准确，灵敏，可重现，可用于从原料药和药物制剂中估算柠檬酸羟乙胺。

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