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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Could the cancer be a chronic immune disorder? rather than a serious malignant disease
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Could the cancer be a chronic immune disorder? rather than a serious malignant disease

机译：癌症可能是慢性免疫疾病吗？而不是严重的恶性疾病

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Despite what is known about the cancer as a malignant dangerous disease treated classically by surgery, chemotherapy and radiotherapy which have a drastic consequences, demaging effect on rapidly growing immune cells e.g. bone marrow which may worsen the condition further. Cancer could be treated softly with immune modulating agents targeting specific key regulaters through the cell cycle e.g. COX2, PI3K, uPA, Hsp90, MIF, mTOR, IKK-b….etc. if cancer be a syndrom of immune disorder rather than a real disease, so treatment of the syndrom will not cure the disorder which may explain the reason of inappropriateness of cancer classical therapies. The new strategy depends on considering cancer as a chronic immune disorder that is started with inflammation followed by progression of cancer as a syndrom. Only treatment the cause will relapse the whole sequence and will cease the progress of the disease. Dealing with cancer as a chronic inflammatory disease will change the view and decline the use of destructive classical cancer remedies. Furthermore, this strategy will reduce the suffer of the cancer patient and uphold the immune system which is the first selective barrier on further progression of cancer.
机译：尽管已知癌症是一种恶性危险疾病，经典地通过手术，化学疗法和放射疗法来治疗，这具有严重的后果，对快速生长的免疫细胞例如免疫球蛋白造成破坏作用。骨髓可能会使病情进一步恶化。在整个细胞周期中，可用靶向特定关键调节因子的免疫调节剂轻柔地治疗癌症。 COX2，PI3K，uPA，Hsp90，MIF，mTOR，IKK-b….etc等。如果癌症是免疫疾病的综合症而不是真正的疾病，那么对该综合症的治疗将无法治愈该疾病，这可能解释了癌症经典疗法不当的原因。新策略取决于将癌症视为一种慢性免疫疾病，该疾病始于炎症，随后癌症发展为综合征。只有治疗病因才能使整个过程复发，并且将停止疾病的发展。将癌症作为一种慢性炎性疾病进行治疗将改变人们的观点，并减少使用破坏性的经典癌症疗法。此外，该策略将减少癌症患者的痛苦并维持免疫系统，这是癌症进一步发展的第一个选择性障碍。

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