Effect of Eucalyptus Camaldulensis Extracts on Leishmania major In Vitro and In Vivo

Hind Mahdi Jarallah; Abdul Hussein Hubash; Abdul-Mohsin Hamed Jassim

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Effect of Eucalyptus Camaldulensis Extracts on Leishmania major In Vitro and In Vivo

机译：桉树提取物对利什曼原虫的体内和体外作用

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The leaves extract of Eucalyptus camaldulensis (aqueous, alcoholic and oils) were studied as antileishmanial inhibition on Leishmania major promastigotes form. Oils were more active against promastigotes than aqueous and alcoholic extract, thus, the LD50 for oils, alcoholic and aqueous extract was (0.602, 3.630 and 4.786) mg/ml respectively. Oils and alcoholic extract were used by topical application for treated BALB/c mice experimentally infected with L. major, on the footpad thickness and mice tail base ulcers.

机译：研究了桉树（水，酒精和油类）的叶提取物对利什曼原虫主要前鞭毛体形式的抗菊苣抑制作用。油类对前鞭毛体的活性比水和醇类提取物高，因此，油，醇和水提取物的半数致死剂量分别为（0.602、3.630和4.786）mg / ml。在足垫厚度和小鼠尾巴基部溃疡上，通过局部应用将油和酒精提取物局部用于经实验感染大麦芽孢杆菌的经处理的BALB / c小鼠。

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《Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry》 |2017年第12期|共6页
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Hind Mahdi Jarallah; Abdul Hussein Hubash; Abdul-Mohsin Hamed Jassim;
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中图分类化学;
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Effect of Eucalyptus Camaldulensis Extracts on Leishmania major In Vitro and In Vivo

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