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Comparison of two intravenous sedation techniques for use in pediatric dentistry: A randomized controlled trial

机译：两种用于儿科牙科的静脉镇静技术的比较：一项随机对照试验

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Background . Psychological methods are the preferred behavior management techniques (BMTs) for children in the dental clinical set. However, sometimes they are not successful. On such occasions, pharmacological methods can be good alternatives. Intravenous sedation is one of these methods, which are very useful in behavior management. It is highly effective when applied appropriately. Objectives . The aim of this study was to evaluate the efficacy of intravenous sedation using dexmedetomidine in comparison with ketamine and atropine in uncooperative children during dental treatment. Material and Methods . The study was performed on 40 healthy uncooperative children aged 2–6 years. They were equally and randomly divided into 2 groups: group D – intravenous dexmedetomidine with a loading dose of 1 μg/kg body weight (b.w.), which was followed by 0.2 μg/kg b.w./h via continuous infusion; and group K – intravenous ketamine 2 mg/kg b.w. with atropine 0.01 mg/kg b.w. Vital signs, recovery time and adverse effects were all recorded. Behavior was also evaluated using the Ohio State University Behavioral Rating Scale (OSUBRS). Results . Statistically significant differences appeared in the degree of behavior between the 2 groups (p = 0.03). Group D did better than group K. The mean recovery time was shorter in group D than in group K, but there were no statistically significant differences (p = 0.12). No side effects, episodes of cardiovascular or respiratory instability were reported in either group. Conclusion . The use of intravenous sedation in managing uncooperative children is more effective with dexmedetomidine than with ketamine. The addition of atropine as an adjunct to intravenous ketamine sedation helps in preventing complications.
机译：背景 。心理方法是牙科临床应用中儿童首选的行为管理技术（BMT）。但是，有时它们并不成功。在这种情况下，药理方法可能是不错的选择。静脉镇静是这些方法之一，在行为管理中非常有用。适当地使用它会非常有效。目标。这项研究的目的是评估在牙科治疗期间不合作的儿童中，使用右美托咪定与氯胺酮和阿托品进行静脉镇静的疗效。材料与方法 。该研究是针对40名2至6岁的健康不合作儿童进行的。将它们均等地随机分为两组：D组–静脉内右美托咪定，负荷剂量为1μg/ kg体重（b.w.），然后通过连续输注以0.2μg/ kg b.w./h进行; K组–静脉氯胺酮2 mg / kg体重。阿托品0.01 mg / kg b.w.记录生命体征，恢复时间和不良反应。行为也使用俄亥俄州立大学行为评估量表（OSUBRS）进行了评估。结果。两组之间的行为程度差异有统计学意义（p = 0.03）。 D组的表现优于K组。D组的平均恢复时间短于K组，但无统计学差异（p = 0.12）。两组均无副作用，心血管或呼吸系统不稳定的报道。结论。与非氯胺酮相比，右美托咪定对不合作儿童的静脉镇静效果更好。在静脉注射氯胺酮镇静剂中加入阿托品有助于预防并发症。

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