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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Antioxidant activity and total phenolic contentof ethyl acetate extract and fractions of Lantana camara L.leaf
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Antioxidant activity and total phenolic contentof ethyl acetate extract and fractions of Lantana camara L.leaf

机译:乙酸乙酯提取物和马tana丹叶的馏分的抗氧化活性和总酚含量。

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The ethyl acetate extract of Lantana camara L. was subjected in investigation of its antioxidant properties by DPPH method. The concentrated ethyl acetate extract of Lantana camara L. was column chromatographed by separation gradien polarity (SGP) method using silica gel as the stationary phase where is hexane, ethyl acetate and methanol selected as the mobile phases. Seven fractions were obtained, each fractions among them were subjected in investigation of its antioxidant properties and total phenolic content. This studies demonstrated thatIC50 value of Lantana camara L. extractwas found to be 36.18 mg/L with a total phenolic content was 2419.6 GAE. And IC50 value and total phenolic content of each fractions were found to be: Fraction A (132.62 mg/L and237.8 GAE), Fraction B (113.51 mg/L and589.4 GAE), Fraction C (85.23 mg/L and995.5 GAE), Fraction D (81.26 mg/L and1041 GAE), Fraction E (24.83 mg/L and3156 GAE), Fraction F (83.50 mg/L and1037.8 GAE), and Fraction G (806.71 mg/L). Based on the IC50, extract ethyl acetate and Fraction Eare highly active antioxidants, fraction C, D, and Fare active antioxidant, fraction A and B moderate antioxidant and fraction G is not active antioxidant. Antioxidant activity is influenced by total phenolic with correlation number was 98.14%.
机译:用DPPH法研究马Lan丹(Lantana camara L.)的乙酸乙酯提取物的抗氧化性能。马separation丹(Lantana camara L.)的浓缩乙酸乙酯萃取物通过分离梯度极性(SGP)法进行柱色谱分离,硅胶为固定相,其中己烷,乙酸乙酯和甲醇为流动相。获得了七个级分,其中每个级分都经过了其抗氧化性能和总酚含量的研究。研究表明,马Lan丹提取物的IC50值为36.18 mg / L,总酚含量为2419.6 GAE。各个馏分的IC50值和总酚含量为:馏分A(132.62 mg / L和237.8 GAE),馏分B(113.51 mg / L和589.4 GAE),馏分C(85.23 mg / L和995)。 5 GAE),馏分D(81.26 mg / L和1041 GAE),馏分E(24.83 mg / L和3156 GAE),馏分F(83.50 mg / L和1037.8 GAE)和馏分G(806.71 mg / L)。根据IC50,提取乙酸乙酯和馏分Eare为高活性抗氧化剂,馏分C,D和Fare活性抗氧化剂,馏分A和B为中等抗氧化剂,馏分G为非活性抗氧化剂。总酚含量对抗氧化活性的影响为98.14%。

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