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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Green synthesis of silver nanoparticles usinglactose sugar andevaluation of their antimicrobial activity
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Green synthesis of silver nanoparticles usinglactose sugar andevaluation of their antimicrobial activity

机译：用乳糖糖绿色合成银纳米颗粒及其抗菌活性评估

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In nanotechnology science several methods of chemic al synthesis of silver nanoparticles (AgNps) are kn own. These methods involve high pressure, temperature and ener gy.Development in the green synthesis of Ag Nps is an important step in the field of application in nanot echnology. Accordingly, researchersare developing g reen methods that are eco-friendly, cost-effective and energy-ef ficient. Herein we report a green approach for the synthesis of AgNps. Thec olloidal silver particles were synthesized by reduction of AgNO 3 with D (+) lactose as a reducing agent .The morphology and structure of synthesized Ag Nps were characterized usingRayleigh scattering, transmission electron microscopy (TEM), UV/Vis spec trophotometry, dynamic light scattering (DLS) and X -ray diffraction method (XRD). Also the Ag Nps in differ ent concentration and shapes wereanalyzed for their antimicrobial activity agansit 4 positive and negat ive bacteriausing agar disc diffusion methodand fun gusFusarium oxysporum cultivated on Potatoes Dextrose Agar medi um (PDA). Results indicated that synthesized Ag Nps are relatively same in size (15 to 40 nm) and almost sp herical.Also resultsshowed that the AgNps had inhib ition activity against testedmicrobials, especially on Staphylococ cus aureus (+), (C 27 :16 ± 0.55 mm)and Fusarium oxysporum (0 to 100%). The effects of concentration and size of the synthesized Ag NPs on antimicrobial activity we re also discussed.
机译：在纳米技术科学中，已知有几种化学合成银纳米颗粒（AgNps）的方法。这些方法涉及高压，高温和高能。Ag Nps绿色合成的发展是纳米技术应用领域的重要一步。因此，研究人员正在开发环保，成本有效和节能的绿色方法。在此，我们报告了一种合成AgNps的绿色方法。以D（+）乳糖为还原剂还原AgNO 3，合成线状银颗粒。利用瑞利散射，透射电镜，紫外可见分光光度法，动态光对合成的Ag Nps的形貌和结构进行表征。散射（DLS）和X射线衍射法（XRD）。还使用琼脂圆盘扩散法和在马铃薯右旋糖琼脂培养基（PDA）上培养的有趣的枯萎病菌，分析了不同浓度和形状的Ag Nps的抗菌活性，可识别4种阳性和阴性细菌。结果表明，合成的Ag Nps的大小相对相同（15至40 nm），并且几乎呈螺旋形分布。此外，结果表明AgNps对被测微生物具有抑制活性，特别是对金黄色葡萄球菌（+）具有抑制作用（C 27:16±0.55毫米）和尖孢镰刀菌（0至100％）。我们还讨论了合成的Ag NP的浓度和大小对抗菌活性的影响。

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