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Diagnosis of Early Gastric Cancer by Magnifying Endoscopy with NBI from Viewpoint of Histological Imaging: Mucosal Patterning in terms of White Zone Visibility and Its Relationship to Histology

机译:从组织学影像学角度通过NBI放大内窥镜诊断早期胃癌:白区可见度和与组织学的关系的粘膜模式

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The diagnosis of early gastric cancer by magnifying endoscopy with NBI is based on two components: microvascular pattern and mucosal pattern. Mucosal patterns are characterized by a whitish edge, which has been named the white zone. Some cancerous areas showing a distinct white zone form clear mucosal patterns, whereas others showing a nondistinct white zone do not form mucosal patterns. The aim of the present study was to clarify the histological differences between these two types of area. In transverse sections of gastric epithelium, the lengths of intervening parts in areas showing a distinct white zone, a nondistinct white zone, and an invisible white zone were measured, and the depths of the crypts in these three types of area were also measured. The intervening parts in areas with a nondistinct or invisible white zone were shorter than those in areas with a distinct white zone (P<0.05), and the crypts in the former areas were shallower than those in the latter (P<0.01). Areas in which the intervening part were long and the crypts deep tended to show a distinct white zone, whereas areas with short intervening parts or shallow crypts tended to show a nondistinct or non-visible white zone.
机译:通过NBI放大内窥镜对早期胃癌的诊断基于两个组成部分:微血管模式和粘膜模式。粘膜模式的特征是发白的边缘,被称为白色区域。一些显示出明显白色区域的癌变区域形成了清晰的粘膜模式,而其他显示出不明显白色区域的癌变区域则没有形成粘膜模式。本研究的目的是阐明这两种类型区域之间的组织学差异。在胃上皮的横断面中,测量显示出明显的白色区域,不明显的白色区域和不可见的白色区域的区域的介入部分的长度,并且还测量这三种类型区域中隐窝的深度。白色区域不明显或不可见的区域的中间部分短于白色区域明显的区域的中间部分(P <0.05),前者的隐窝比后者的隐窝浅(P <0.01)。中间部分较长且隐窝较深的区域往往会显示明显的白色区域,而中间部分较短或隐窝较浅的区域则倾向于显示不明显或不可见的白色区域。

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