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Propofol Sedation for ERCP Procedures: A Dilemna? Observations from an Anesthesia Perspective

机译:ERCP手术中的异丙酚镇静剂:困境?从麻醉角度观察

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Propofol sedation for endoscopic retrograde cholangiopancreatography (ERCP) procedures is a popular current technique that has generated controversy in the medical field. Worldwide, both anesthetic and nonanesthetic personnel administer this form of sedation. Although the American and Canadian societies of gastroenterologists have endorsed the administration of propofol by nonanesthesia personnel, the US Food and Drug Administration (FDA) has not licensed its use in this manner. There is some evidence for the safe use of propofol by nonanesthetic personnel in patients undergoing endoscopy procedures, but there are few randomized trials addressing the safety and efficacy of propofol in patients undergoing ERCP procedures. A serious possible consequence of propofol sedation in patients is that it may result in rapid and unpredictable progression from deep sedation to general anesthesia, and skilled airway support may be required as a rescue measure. Potential complications following deep propofol sedation include hypoxemia and hypotension. Propofol sedation for ERCP procedures is an area of clinical practice where discussion and mutual cooperation between anesthesia and nonanesthesia personnel may enhance patient safety.
机译:内窥镜逆行胰胆管造影术(ERCP)的异丙酚镇静是当前流行的技术,在医学领域引起了争议。在世界范围内,麻醉和非麻醉人员均使用这种镇静剂。尽管美国和加拿大的肠胃病学会认可非麻醉人员对异丙酚的管理,但美国食品和药物管理局(FDA)并未以这种方式许可其使用。有一些证据表明非麻醉人员可以安全地在接受内窥镜检查的患者中使用丙泊酚,但是很少有关于丙泊酚在接受ERCP手术的患者中的安全性和有效性的随机试验。丙泊酚镇静对患者的严重可能后果是,它可能导致从深层镇静到全身麻醉的快速而不可预测的进展,可能需要熟练的气道支持作为抢救措施。丙泊酚深度镇静后的潜在并发症包括低氧血症和低血压。 ERCP手术中的异丙酚镇静是临床实践中的一个领域,麻醉与非麻醉人员之间的讨论和相互合作可以提高患者的安全性。

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