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首页> 外文期刊>Diagnostic and therapeutic endoscopy >Endoscopic-Ultrasound-Guided Tissue Sampling Facilitates the Detection of Local Recurrence and Extra Pelvic Metastasis in Pelvic Urologic Malignancy
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Endoscopic-Ultrasound-Guided Tissue Sampling Facilitates the Detection of Local Recurrence and Extra Pelvic Metastasis in Pelvic Urologic Malignancy

机译：内镜超声引导下的组织采样有助于盆腔泌尿系统恶性肿瘤的局部复发和盆腔外转移的检测

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Pelvic lymph node dissection is the gold standard for assessing nodal disease in prostate or bladder cancer and is superior to CT, MRI and PET staging. Endoscopic ultrasound (EUS) provides an alternative, less invasive method of cytohistologic material acquisition, but its performance in pelvic urologic malignancy is unknown. Therefore, our aim was to evaluate the diagnostic accuracy of EUS guided tissue sampling for these malignancies when compared to a composite cytohistologic and surgical gold standard. A median of 3 FNA passes were performed (n=19patients) revealing a sensitivity, specificity, PPV and NPV of 94.4% (72–99), 100% (2–100), 100% (80–100) and 50% (1–98) respectively. The perirectal space was the most frequently sampled location irrespective of the primary urological cancer origin. Final diagnosis established by EUS tissue sampling included bladder cancer (n=1), bladder cancer local recurrence (n=8), bladder cancer extra pelvic metastases (n=1), prostate cancer (n=2), prostate cancer local recurrence (n=4), prostate cancer extra pelvic metastases (n=1), testicular cancer extra pelvic metastases (n=1) and a benign seminal vesicle (n=1). EUS guided sampling of the gut wall, lymph nodes, or perirectal space yields suitable diagnostic material to establish the presence of primary, local recurrence or extra pelvic metastases of pelvic urologic malignancy.
机译：盆腔淋巴结清扫术是评估前列腺癌或膀胱癌淋巴结疾病的金标准，优于CT，MRI和PET分期。内窥镜超声检查（EUS）提供了另一种侵入性较小的细胞组织学材料采集方法，但其在盆腔泌尿系统恶性肿瘤中的表现尚不清楚。因此，我们的目的是评估与复合细胞组织学和外科手术金标准相比，EUS引导的组织样本对这些恶性肿瘤的诊断准确性。进行了3次FNA通行检查（n = 19位患者），显示敏感性，特异性，PPV和NPV分别为94.4％（72-99），100％（2-100），100％（80-100）和50％（ 1–98）。直肠周围空间是最常采样的位置，而与原发性泌尿系癌症的起源无关。由EUS组织采样确定的最终诊断包括膀胱癌（n = 1），膀胱癌局部复发（n = 8），膀胱癌骨盆外转移（n = 1），前列腺癌（n = 2），前列腺癌局部复发（ n = 4），前列腺癌骨盆外转移（n = 1），睾丸癌骨盆外转移（n = 1）和良性精囊（n = 1）。 EUS指导的肠壁，淋巴结或直肠周围空间采样可产生合适的诊断材料，以建立骨盆泌尿系恶性肿瘤的原发性，局部复发或额外的骨盆转移。

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