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首页> 外文期刊>Diagnostic and therapeutic endoscopy >Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach
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Perioperative and Oncological Outcome of Laparoscopic Resection of Gastrointestinal Stromal Tumour (GIST) of the Stomach

机译：腹腔镜切除胃胃肠道间质瘤（GIST）的围手术期和肿瘤学结果

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Background. Surgery remains the only curative treatment for gastrointestinal stromal tumour (GIST). Resection needs to ensure tumour-free margins while lymphadenectomy is not required. Thus, partial gastric resection is the treatment of choice for small gastric GISTs. Evidence on whether performing resection laparoscopically compromises outcome is limited.Methods. We compiled patients undergoing laparoscopic resection of suspected gastric GIST between 2003 and 2007. Follow-up was performed to obtain information on tumour recurrence.Results. Laparoscopic resection with free margins was performed in 21/22 patients. Histology confirmed GIST in 17 cases, 4 tumours were benign neoplasms. Median operation time and postoperative stay for GIST patients were 130 (range 80–201) mins and 7 (range 5–95) days. Two patients experienced stapler line leakage necessitating surgical revision. After median follow-up of 18 (range 1–53) months, no recurrence occurred.Conclusions. Laparoscopic resection of gastric GISTs yields good perioperative outcomes. Oncologic outcome needs to be assessed with longer follow-up. For posterior lesions, special precaution is needed. Laparoscopic resection could become standard for circumscribed gastric GISTs if necessary precautions for oncological procedures are observed.
机译：背景。手术仍然是治疗胃肠道间质瘤（GIST）的唯一方法。切除需要确保无肿瘤边缘，而无需进行淋巴结清扫术。因此，部分胃切除术是小型胃GIST的治疗选择。关于腹腔镜手术切除是否损害预后的证据有限。我们收集了2003年至2007年间接受腹腔镜手术切除的怀疑胃GIST的患者。对患者进行随访以获取有关肿瘤复发的信息。 21/22例患者行腹腔镜切除术，切缘自由。组织学证实为GIST的17例中，有4例为良性肿瘤。 GIST患者的中位手术时间和术后停留时间为130（80-201）分钟和7（5-95）天。两名患者经历吻合器缝合线渗漏，需要进行手术翻修。在中位随访18（1-53）个月后，未复发。腹腔镜切除胃部GISTs可获得良好的围手术期效果。肿瘤的结局需要更长的随访时间来评估。对于后部病变，需要采取特殊的预防措施。如果观察到必要的肿瘤学预防措施，腹腔镜切除术可能成为限制胃GISTs的标准方法。

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