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首页> 外文期刊>The Egyptian Journal of Hospital Medicine >Assessment of Optic Disc Perfusion in Open Angle Glaucoma (OAG) Using Optical Coherence Tomography Angiography (OCTA)
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Assessment of Optic Disc Perfusion in Open Angle Glaucoma (OAG) Using Optical Coherence Tomography Angiography (OCTA)

机译：光学相干断层扫描血管造影（OCTA）评估开角型青光眼（OAG）的视盘灌注

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Background: glaucoma is a major disease that potentially results in irreversible blindness, some prospective studies demonstrated that in primary open-angle glaucoma (POAG), blood flow is diminished in the ophthalmic, retinal, choroid and retro-bulbar circulations. Aim of the Work: this study aimed to compare Optic disc perfusion in normal healthy persons with that of Open Angle Glaucoma (OAG) patients by using Optical Coherence Tomography Angiography (OCTA) and to see if a correlation exists between optic disc perfusion, visual field changes and retinal nerve fiber layer thickness in normal healthy persons and in OAG patients. Patients and Methods: we did an analysis of optic disc perfusion in two groups of normal healthy persons and primary open angle glaucoma patients who were previously diagnosed and attended follow up in outpatient clinic in Sayed Galal University Hospital located in Cairo. In our study we included 22 eyes of 12 people, (10 normal eyes and 12 Open angle glaucoma patients eyes) aged between 20 and 78 years old. Results: there was a statistically significant relationship between optic disc perfusion and glaucoma group in comparison with normal group, thus in normal group the optic disc perfusion indicated good optic disc perfusion which was significantly lower in glaucoma group. Also we discovered that there was a statistically significant correlation between optic disc perfusion with (Visual field changes and RNFL thickness). Conclusion: optic disc perfusion assessment by using OCT angiography could be beneficial in evaluation of glaucoma and assessment of disease progression and it's follow up together with Visual Field assessment and clinical examination.
机译：背景：青光眼是可能导致不可逆性失明的主要疾病，一些前瞻性研究表明，在原发性开角型青光眼（POAG）中，眼，视网膜，脉络膜和后球后循环的血流减少。工作目的：本研究旨在通过光学相干断层扫描血管造影术（OCTA）比较正常健康人和开角型青光眼（OAG）患者的视盘灌注，并观察视盘灌注与视野之间是否存在相关性正常健康人和OAG患者的眼底变化和视网膜神经纤维层厚度。患者和方法：我们对两组先前被诊断并曾在开罗萨伊德加拉尔大学医院门诊就诊的正常健康人和原发性开角型青光眼患者的视盘灌注进行了分析。在我们的研究中，我们纳入了12人中的22眼（10例正常眼和12例开角型青光眼患者眼），年龄在20至78岁之间。结果：与正常组相比，视盘灌注与青光眼组之间存在统计学上的显着关系，因此在正常组中，视盘灌注表明良好的视盘灌注，而在青光眼组中则明显较低。我们还发现，视盘灌注与（视野变化和RNFL厚度）之间存在统计学上的显着相关性。结论：利用OCT血管造影进行视盘灌注评估可能对青光眼评估和疾病进展评估有帮助，并应与视野评估和临床检查相结合。

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