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首页> 外文期刊>Drugs - Real World Outcomes >Characterisation of Drug-Related Problems and Associated Factors at a Clinical Pharmacist Service-Na?ve Hospital in Northern Sweden
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Characterisation of Drug-Related Problems and Associated Factors at a Clinical Pharmacist Service-Na?ve Hospital in Northern Sweden

机译：瑞典北部临床药剂师服务-天真的医院的药物相关问题和相关因素的表征

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BackgroundPolypharmacy and increased sensitivity to side effects cause adverse drug events, drug–drug interactions and medication errors in the elderly. ObjectiveThe objective of this study was to investigate the prevalence and type of drug-related problems and associated factors among patients admitted to a clinical pharmacist service-na?ve medical ward in an inland hospital in northern Sweden. MethodsDuring September–November 2015 and February–April 2016, clinical pharmacists working as part of a ward team on the medical ward conducted 103 medication reviews. Drug-related problems were identified and classified. Associated factors, drug classes and specific drugs involved were also investigated. ResultsThe clinical pharmacists identified 133 drug-related problems in 66% [68/103] of the study population. The most common drug-related problems in this study were inappropriate drug use and interactions. Cardiovascular drugs and psychotropic drugs were most commonly involved. Drug-related problems were more frequently observed at higher age, increasing number of drugs prescribed and in patients with reduced renal function. In the multivariate analysis, only the number of prescribed drugs was still significant. ConclusionDrug-related problems were commonly observed among patients admitted to the medical ward. Medication reviews conducted by clinical pharmacists as part of a ward team resulted in several interventions to improve the patients’ drug treatment.
机译：背景多药和对副作用的敏感性增加会导致老年人出现不良药物事件，药物相互作用以及药物错误。目的这项研究的目的是调查瑞典北部内陆医院的临床药剂师初治医疗病房的患者中与药物有关的问题的患病率和类型以及相关因素。方法在2015年9月至11月和2016年2月至4月期间，作为该病房病房团队成员的临床药剂师进行了103次用药审查。与毒品有关的问题得到了识别和分类。还调查了相关因素，药物类别和涉及的特定药物。结果临床药师在66％[68/103]的研究人群中发现了133个与药物相关的问题。在这项研究中，最常见的药物相关问题是药物使用和相互作用不当。最常见的是心血管药物和精神药物。在较高的年龄，增加的处方药数量以及肾功能减退的患者中更经常观察到与药物有关的问题。在多变量分析中，仅处方药的数量仍然很大。结论收治病房的患者普遍存在药物相关问题。由临床药剂师组成的病房小组对药物进行了审查，采取了多种干预措施来改善患者的药物治疗。

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