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Compounds isolated from Harpalyce brasiliana Benth and their pharmacological properties

机译:从巴西pa中分离出的化合物及其药理特性

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Harpalyce brasiliana Benth, known as snakeroot, is one of the most popular herbal medicines against snakebite in South America. A hydroalcoholic solution is traditionally prepared from the roots of H. brasiliana. In the last two decades, understanding the pharmacological properties and the possible medicinal applications of H. brasiliana has increased considerably. H. brasiliana has antivenom activity and anticarcinogenic, antimicrobial and antioxidant properties. Various in vitro and in vivo studies have shown H. brasiliana’s diverse biological properties and its potential for disease treatment. The different biological effects of this plant may be attributable to the presence of secondary active metabolites such as pterocarpans, triterpenoids, chalcones and flavonoids. This overview presents different aspects of this plant and the pharmacological properties of its compounds through a review of the available literature. The results support the use of H. brasiliana in the treatment of snakebite and its potential for treatment of other diseases in folk medicine.
机译:巴西蛇藤(Harpalyce brasiliana Benth)被称为蛇根,是南美最受欢迎的对抗蛇咬的草药之一。传统上,从巴西芸苔的根中制备水醇溶液。在过去的二十年中,对巴西布鲁氏菌的药理性质和可能的医学应用的了解已大大增加。 H. brasiliana具有抗蛇毒活性,并具有抗癌,抗微生物和抗氧化的特性。各种体外和体内研究表明,巴西布鲁氏菌具有多种多样的生物学特性及其在疾病治疗中的潜力。该植物的不同生物学效应可能归因于次生活性代谢产物的存在,例如,罗汉果,三萜类化合物,查耳酮和类黄酮。该概述通过查阅现有文献介绍了该植物的不同方面及其化合物的药理特性。研究结果支持了H. brasiliana在蛇咬病治疗中的应用及其在民间医学中治疗其他疾病的潜力。

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