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首页> 外文期刊>Drug Safety - Case Reports >Fournier’s Gangrene in a Patient with Type 2 Diabetes Mellitus Treated with Empagliflozin: A Case Report
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Fournier’s Gangrene in a Patient with Type 2 Diabetes Mellitus Treated with Empagliflozin: A Case Report

机译：Empagliflozin治疗的2型糖尿病患者中的Fournier坏疽：一个病例报告

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Abstract Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been reported as possibly associated with Fournier’s gangrene (FG). This case report describes a 34-year-old Japanese man who was diagnosed with FG after the administration of empagliflozin for type 2 diabetes mellitus (T2DM). He presented with pain and swelling in the perineum and groin 142?days after initiating empagliflozin. The clinical features, laboratory data, and computed tomographic findings were consistent with FG. Surgical drainage and debridement of necrotic tissues were performed immediately after admission to our hospital. The patient had no complications of diabetes before the onset of FG. Glycemic management was good at the time of FG onset. This case suggests a possible association between empagliflozin and FG. We report a case of FG in a patient during a period of good glycemic management following treatment with empagliflozin. We recommend further awareness of this relationship and suggest the need for additional research.
机译：摘要据报道，钠葡萄糖共转运蛋白2（SGLT2）抑制剂可能与Fournier的坏疽（FG）有关。该病例报告描述了一名34岁的日本男子，他在服用恩帕格列净治疗2型糖尿病（T2DM）后被诊断出FG。在开始使用恩帕格列净后142天，他的会阴部和腹股沟出现疼痛和肿胀。临床特征，实验室数据和计算机断层扫描结果与FG一致。入院后立即进行外科引流和坏死组织清创术。该患者在FG发作之前没有糖尿病并发症。 FG发作时血糖管理良好。这种情况表明，依帕列净与FG之间可能存在关联。我们报告了在依帕列净治疗后良好的血糖控制期间，一名患者的FG病例。我们建议您进一步了解这种关系，并建议需要进行其他研究。

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